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  1. The number of young patients with cardiac disease has recently increased. To describe the electrocardiogram characteristics and identify the possible factors affecting the characteristics in early life might b...

    Authors: Shingo Nakashima, Mami Ishikuro, Keiko Murakami, Fumihiko Ueno, Aoi Noda, Tomomi Onuma, Fumiko Matsuzaki, Taku Obara and Shinichi Kuriyama
    Citation: BMC Pediatrics 2025 25:697
  2. Neonatal mortality remains a major global health concern, with birth asphyxia responsible for nearly one-quarter of these deaths. Effective and timely neonatal resuscitation by skilled healthcare providers is ...

    Authors: Mesfin Wubishet, Tadesse Assefa, Tesfa G/Meskel, Hiwot Zelalem and Betre Shimelis
    Citation: BMC Pediatrics 2025 25:696
  3. This study sampled Chinese families of children with acute leukemia to assess their levels of anxiety and explore whether those levels were associated with social support levels and coping style. The study als...

    Authors: Jiani Tan, Kaili Wu and Jingjing Ma
    Citation: BMC Pediatrics 2025 25:695
  4. Acute abdominal pain is a common yet diagnostically challenging presentation in pediatric emergency care due to nonspecific symptoms. While ultrasound offers a safe and accessible diagnostic tool, its clinical...

    Authors: Mehdi Kavari, Robab Sadegh and Reza Golchin Vafa
    Citation: BMC Pediatrics 2025 25:694
  5. Vitamin A deficiency remains a critical public health issue in Ethiopian children under five years, significantly contributing to increased morbidity and mortality. Despite national supplementation programs, c...

    Authors: Berhanu Wale Yirdaw, Abrham Maru Moges, Setargew Kebie Awoke, Maritu Ayalew Agmas, Asmare Yimer Mekonen, Abusew Yehuala Abebe, Ashebir Mamay Gebiru, Jember Ayelgne Beyene and Bimrew Bayuh Yimer
    Citation: BMC Pediatrics 2025 25:693
  6. The present study was conducted as a randomized controlled trial to investigate the combined impact of rituximab and target care on efficacy, quality of life, adverse reactions, and recurrence rate among child...

    Authors: Lanfen He, Huazhen Mei, Yan Gu, Zeng Liu, Lian Yang, Xiaolu Li, Xiaofeng Wang and Ting Xu
    Citation: BMC Pediatrics 2025 25:691
  7. Firearms are the leading cause of death in children in the United States. Rates of firearm injury and death are rising among young children, ages 0–5 years, yet data-driven prevention strategies are lacking. T...

    Authors: Alison L. Miller, Wadad Itani, Hurley Riley, Ezekiel Medina, Odalys Arbelaez, Julia Plawker, Andrew Hashikawa, Daniel Lee, Justin Heinze, Cynthia Ewell-Foster, Rebeccah Sokol and Hsing-Fang Hsieh
    Citation: BMC Pediatrics 2025 25:690
  8. Following the termination of China’s dynamic zero-COVID policy on December 7, 2022, a substantial rise in COVID-19 infections among infants and toddlers was observed. Clinical practice revealed that many infec...

    Authors: Zongyuan Liu, Mengyue Li, Jiping Lv, Yajie Wang, Debin Yang, Linan Gao, Yuanzhe Li and Bo Hu
    Citation: BMC Pediatrics 2025 25:689
  9. The Omicron variant has become the predominant strain globally, yet pediatric data on COVID-19-associated acute encephalopathy (AE) remain scarce. This study aimed to characterize the clinical features and out...

    Authors: SiYuan Huang, Jing Chen, Fang Li, Wei Li, Ning Li, YuChun Yan, Dong Qu and Shuang Liu
    Citation: BMC Pediatrics 2025 25:688
  10. Parents’ role as primary decision-makers in medication administration is essential to ensuring proper antibiotic use. Despite its significance, only a few studies have delved into parental perspectives. Theref...

    Authors: Dian Ayu Eka Pitaloka, Ariani Insyirah, Anisa Nabilah Oktariani, Cut Ainul Mardhiyyah and Nayla Majeda Alfarafisa
    Citation: BMC Pediatrics 2025 25:687
  11. In Canada, Indigenous peoples are disproportionately affected by type 2 diabetes (T2D) and related complications due to the lasting impacts of colonization, cultural dispossession, and social inequities. Early...

    Authors: Shelley Spurr, Jill M. G. Bally, Meridith Burles, Cathy Langdon, Allison Cammer and Helen Tootoosis
    Citation: BMC Pediatrics 2025 25:686
  12. Preterm birth is the leading cause of childhood mortality, with respiratory distress syndrome as the predominant aetiology. Initiating continuous positive airways pressure (CPAP) immediately after birth may re...

    Authors: Agnes Napyo, Alice Nakiyemba, Martha Muduwa, John M. Ssenkusu, Francis Okello, Cornelia Hagmann, Judith Namuyonga, Adam Hewitt-Smith, Kate Loe, Abongo Grace, Amorut Denis, Julius Wandabwa, Peter Olupot-Olupot and Kathy Burgoine
    Citation: BMC Pediatrics 2025 25:685
  13. Early oral propranolol for infantile hemangioma (IH) can improve the success rate. However, few studies have been conducted on the specific age threshold for initiating treatment with propranolol. This study a...

    Authors: Kaizhi Zhang, Tong Qiu, Jiangyuan Zhou, Xue Gong, Zixin Zhang, Shanshan Xiang and Yi Ji
    Citation: BMC Pediatrics 2025 25:684
  14. Calcifying fibrous tumor (CFT) is a rare benign mesenchymal tumor. Primary small intestinal CFT causing intestinal obstruction in children is exceptionally rare. Preoperative diagnosis remains challenging due ...

    Authors: Zesheng Yang, Xiaoying Xie, Shicheng Wang, Weijun Xu, Guanghua Pei and Jun Wan
    Citation: BMC Pediatrics 2025 25:683
  15. With increasing survival rates following pediatric intensive care unit (PICU) hospitalization, assessing functional outcomes is imperative. We compared children’s psychosocial and adaptive functioning six week...

    Authors: Reham I. Abdelmageed, Azza M. Youssef, Sondos M. Magdy, Ahmed N. Nasr and Asmaa W. Abdelaziz
    Citation: BMC Pediatrics 2025 25:682
  16. Stunting, a significant form of chronic undernutrition, affects millions of children under five worldwide and poses substantial challenges to physical, cognitive, and socioeconomic development—particularly in ...

    Authors: Abdelaziz Hendy, Rasha Kadri Ibrahim, Sally Mohammed Farghaly Abdelaliem, Ahmed Zaher, Sameer A. Alkubati, Rabab Gad Abd El-kader and Ahmed Hendy
    Citation: BMC Pediatrics 2025 25:681
  17. Type 1 diabetes (T1D) is a chronic autoimmune condition potentially influenced by environmental factors, including exposure to heavy metals such as lead, mercury, and cadmium.

    Authors: Hoda A. Atwa, Mohamed S. Hemeda, Rania M. Farh, Amany A. Khafagy, Basma M. Abdelaziz and Marwa A. Ibrahim
    Citation: BMC Pediatrics 2025 25:680
  18. Red blood cell (RBC) transfusion is a common intervention for anemia in preterm infants; however, its association with bronchopulmonary dysplasia (BPD) remains debated. While biological mechanisms suggest pote...

    Authors: Zhenhai Zhang, Shengkai Lu, Xiaoyan Fang and Hao Zhang
    Citation: BMC Pediatrics 2025 25:679
  19. Adequate sleep is crucial for children’s health, especially for children with ADHD and concurrent sleep problems. There is a need for more studies focusing on sleep problems in children with ADHD as these prob...

    Authors: Julia S. Malmborg, Josefine Tuvesson, Ingrid Larsson, Petra Svedberg, Jens Nygren, Håkan Jarbin and Annelie Lindholm
    Citation: BMC Pediatrics 2025 25:678
  20. This study aimed to evaluate the impact of asthma severity on biventricular cardiac functions using tissue Doppler imaging (TDI), two-dimensional speckle tracking echocardiography (2D-STE), and three-dimension...

    Authors: Rehab Elmeazawy, Osama El Razaky, Doaa El Amrousy and Al Shimaa Badreldeen
    Citation: BMC Pediatrics 2025 25:677
  21. Childhood disability can have a negative effect on children’s general productivity and quality of life. It is a significant social and economic issue worldwide. This study’s primary goal is to examine the effe...

    Authors: Efty Islam Arpon, Sujan Kumar Naha, Sazzad Hossain Mithu and Jamal Uddin
    Citation: BMC Pediatrics 2025 25:675
  22. To assess the clinical service provision of neonatal follow-up services in the UK in line with UK National Institute for Health and Care Excellence (NICE) guideline NG72, ‘Developmental follow-up of children a...

    Authors: Claire Marcroft, Hilary Cruickshank, Samantha Johnson, Catherine Exley, Niina Kolehmainen, Richard Thomson and Anna Basu
    Citation: BMC Pediatrics 2025 25:674
  23. It has been proposed that early-life screen use can impact the development of attention deficit hyperactivity disorder (ADHD) symptoms. Some studies have supported a weak association between higher levels of s...

    Authors: Aja Murray, Hannah Casey, Helen Wright, Xinxin Zhu, Yi Yang, Xuefei Li, Zhuoni Xiao, Josiah King, Kasia Kostyrka-Allchorne and Edmund Sonuga-Barke
    Citation: BMC Pediatrics 2025 25:673
  24. Acute splenic sequestration crisis (ASSC) is a potentially life-threatening complication of sickle cell disease (SCD). Previous studies have shown that patients who carry the African sickle gene haplotypes hav...

    Authors: Abdalla Mohamed Zayed, Sulaiman Almohaimeed, Turki Alotaibi, Hossam Aldosari, Tahani Alotaibi, Basheer Ahmed, Khalid Abdullah, Yasser Awadallah, Shangrila Joy Ancheta, Zechariah Jebakumar Arulantham, Taha Khattab, Anfal Alrwili, Asalah Alhazmi, Eman Al Ghamdi and Shadin Alamrah
    Citation: BMC Pediatrics 2025 25:672
  25. Structured diabetes education plays a crucial role in the management of Type 1 Diabetes (T1D), especially with advanced technologies such as continuous subcutaneous insulin infusion (CSII). This study evaluate...

    Authors: Mona Hassan, Mahmoud ElHelaly, Nora Badawi, Mariam Nader and Radwa Shamma
    Citation: BMC Pediatrics 2025 25:670
  26. Transnasal humidified rapid-insufflation ventilatory exchange is a novel ventilation modality which can provide very high flow (up to 70 l/min) heated and humidified gas with adjustable temperatures (31–37 °C)...

    Authors: He Geng, Cuicui Yao, Lixin Wu, Jinhong Zhong, Ruoqiao Wang and Fang Chen
    Citation: BMC Pediatrics 2025 25:669
  27. Although the neutrophil-to-lymphocyte ratio (NLR) has demonstrated diagnostic utility in appendicitis, its predictive value for postoperative recovery outcomes remains uncertain. This investigation sought to e...

    Authors: Ming Liu, Yunpeng Gou and Ping Yang
    Citation: BMC Pediatrics 2025 25:668
  28. Nigeria remains one of the highest burden bearers of snakebite envenoming in sub-Saharan Africa. In Northeastern Nigeria, where agricultural practice, livestock herding and outdoor play—especially during the d...

    Authors: Nicholas Amani Hamman, Aashna Uppal, Ezra Garbeya Daniel, Nuhu Mohammed, Nyadah Nicholas, Abubakar Saidu Ballah, Nasiru Bappayo, Bello Abdulkadir, Bala Lawan, Joshua Abubakar Difa and Elon Warnnow Isaac
    Citation: BMC Pediatrics 2025 25:666
  29. Despite significant advancements in neonatal care, mid to late preterm infants (32–36 weeks’ gestation) remain at high risk for recurrent respiratory tract infections (RRTIs). Current prevention strategies are...

    Authors: Hongli Yang, Yuqi Wang, Linlin Fu, Ximeng Zhang and Congcong Zhi
    Citation: BMC Pediatrics 2025 25:665
  30. Several studies have shown that maladaptive eating behaviors in childhood predict greater risk for eating disorders in adolescence. Whether or not maladaptive eating behaviors could represent developmental ris...

    Authors: Rachel Dufour, Édith Breton, Sylvana M. Côté, Lise Dubois, Frank Vitaro, Michel Boivin, Richard E. Tremblay and Linda Booij
    Citation: BMC Pediatrics 2025 25:663
  31. Juvenile idiopathic arthritis (JIA) is a heterogeneous complex autoimmune disorder that occurs in childhood and is characterized by chronic joint inflammation. Serum ferritin, an acute phase reactant, is eleva...

    Authors: Nitin Das, Taskina Mosleh and Manik Kumar Talukder
    Citation: BMC Pediatrics 2025 25:662
  32. The main treatments for biliary dilatation (BD) are surgical resection and choledochojejunostomy. However, various factors lead to the postponement of early surgical intervention in pediatric BD patients. This...

    Authors: Sheng Ding, Jing-Qing Zeng, Zhao-Hui Deng, Tian-Ao Zhang and Biao Gong
    Citation: BMC Pediatrics 2025 25:660
  33. Most preterm infants with a gestational age < 32 weeks in the neonatal intensive care unit (NICU) undergo blood transfusion therapy during their hospital stay to enhance their oxygen-carrying capacity and impr...

    Authors: Yahui Zhang, Weiwei Zhu, Qing Du, Lingli Chen, Jianqiu Huang and Yunfeng Liu
    Citation: BMC Pediatrics 2025 25:659
  34. Intravenous immunoglobulin (IVIG) resistance of Kawasaki disease (KD) patients have a heightened risk of coronary artery lesions. We aimed to explore the predictive factors of IVIG resistance of KD from Shando...

    Authors: Gang Luo, Huashu Liu, Zhixin Li, Zhixian Ji, Sibao Wang and Silin Pan
    Citation: BMC Pediatrics 2025 25:658
  35. Thirst is a prevalent and intense symptom experienced in children after congenital heart disease (CHD) surgery. Identifying independent risk factors for thirst is crucial for early prevention and management. T...

    Authors: Yaqin Chen, Xuecui Zhang, Ting Liang, Qiong Pan, Yanchun Peng, Liangwan Chen and Yanjuan Lin
    Citation: BMC Pediatrics 2025 25:657
  36. The cornerstone of achieving remission for epileptic patients is anti-seizure medication (ASM). An effective anti-seizure pharmaceutical therapy can lead to seizure independence by reducing or eliminating symp...

    Authors: Tigabu Eskeziya Zerihun, Fisseha Nigussie Dagnew, Sisay Sitotaw Anberbr, Getachew Yitayew Tarekegn and Abel Temeche Kassaw
    Citation: BMC Pediatrics 2025 25:656
  37. The psychological issues associated with idiopathic central precocious puberty (ICPP) in girls remain a contentious topic, particularly regarding the necessity and effectiveness of psychological interventions ...

    Authors: Jiao Chen, Lihong Cao, Xiaosa Chen, Xinjuan Zhou, Qingqing Yu, Wenqian Yang and Hong Chen
    Citation: BMC Pediatrics 2025 25:655
  38. We aimed to use the Wide-range Assessment of Vision-related Essential Skills (WAVES) to evaluate the visual perception of Japanese schoolchildren born weighing < 1500 g, who did not need support class and had ...

    Authors: Miho Fukui, Shuichi Shimakawa, Tomohito Okumura, Hikaru Tsuda-Kitahara and Akira Ashida
    Citation: BMC Pediatrics 2025 25:654
  39. With the increasing prevalence of abdominal obesity among children and adolescents, identifying easily measurable, safe, efficient, low-cost, and highly effective indicators is crucial in public health managem...

    Authors: Fang Liu, Shuxian Yuan, Xiaocui Ma, Yangshiyu Li, Shiqi Wang, Yifan Lin, Yongxing Chen and Haiyan Wei
    Citation: BMC Pediatrics 2025 25:651
  40. Active parents may have more active children, as parents act as role models for their children’s physical activity (PA). Parents can facilitate access to PA, provide information, validate physical-sport behavi...

    Authors: Fernando Rodríguez-Rodríguez, Sam Hernández-Jaña, José Castro-Piñero, Javier Brazo-Sayavera, Jaime Carcamo-Oyarzun and Ryan E. Rhodes
    Citation: BMC Pediatrics 2025 25:650
  41. Rabies is a fatal viral infection with clinical presentation that can mimic other neurological disorders, such as Guillain-Barre Syndrome (GBS). Both conditions can present in early stages with same signs, inc...

    Authors: Mahmoud N. Khadra, Wasef Abdat, Maysa Alawneh, Abdulkareem Saymeh, Ahmed Abushama and Issa Alawneh
    Citation: BMC Pediatrics 2025 25:648
  42. Pediatric tuberculosis is a major global public health challenge, with reliable diagnosis being a main obstacle to identifying and treating affected children. New and improved diagnostics, ideally on non-sputu...

    Authors: Rinn Song, Else Margreet Bijker, Grace Kisitu, Emily Douglass, Emmanuel Nasinghe, Francesca Wanda Basile, Nisreen Khambati, Adam Penn-Nicholson, Morten Ruhwald, Soyeon Kim, Nathan Mudrak, Nandini Dendukuri, César Ugarte-Gil, Padmini Salgame, David Alland, Susan E. Dorman…
    Citation: BMC Pediatrics 2025 25:647

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