About EMDB
The Electron Microscopy Data Bank (EMDB) is a public repository for cryogenic-sample Electron Microscopy (cryoEM) volumes and representative tomograms of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, helical reconstruction, electron tomography, subtomogram averaging, and electron crystallography (for more information, see the EMDB Policies).
EMDB was founded at EMBL-EBI in 2002 under the leadership of Kim Henrick. From 2007, the archive has been operated jointly by EMBL-EBI and the Research Collaboratory for Structural Bioinformatics (RCSB)a. In 2013, the Protein Data Bank Japan (PDBj) also became involved in EMDB. As of the first of January, 2021, EMDB is an archive operated under the aegis of the Worldwide Protein Data Bank (wwPDB), and has also joined that organisation as a full member.
Results of cryo-EM studies are archived in three collaborating archives:
- EMDB stores the processed 3D volumes and tomograms;
- PDB stores any atomic models that have been constructed based on EMDB data;
- EMPIAR stores the raw EM data underpinning the data in EMDB/PDB.
Data for EMDB and PDB can be deposited through the wwPDB deposition and annotation system OneDep.
EMPIAR (Electron Microscopy Public Image Archive) is a companion archive to EMDB, founded at and operated by EMBL-EBI, and with a mirror site at PDBj.
Citing EMDB
Please cite the following publication in your papers and on websites: The wwPDB Consortium, EMDB—the Electron Microscopy Data Bank, Nucleic Acids Research, Volume 52, Issue D1, 5 January 2024, Pages D456–D465, https://doi.org/10.1093/nar/gkad1019
To cite individual entries, please quote the EMDB accession code(s) and cite the original publication(s) in which the entries are described.
EMDB logos and branding should not be used on public-facing websites unless explicit prior permission has been obtained from us. However, if you want to use an EMDB logo in a presentation or report, you can use the images in the following table royalty-free and without the need to obtain prior permission from us.
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Please see our FAQ, Policies, description of the EMDB data model, or contact the EMDB helpdesk.
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The work on EMDB at EMBL-EBI has been funded in the past by the European Commission, NIH, UKRI-BBSRC and EMBL-EBI (through the EMBL member states). It is currently funded by the Wellcome Trust and EMBL-EBI.
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Recent Entries
(Show all)Structure of Trypanosoma cruzi Prolyl Oligopeptidase in the close state
Cryo-EM structure of chalcone synthase (CHS) from Physcomitrella patens in the presence of CHIL
Cryo-EM structure of human Mre11-Rad50-Nbs1 (MRN) complex bound to DNA and telomeric factor TRF2 fragment (438-542)
Cryo-EM structure of human Mre11-Rad50 (MR) complex bound to DNA and telomeric factor TRF2 fragment (438-542)
Cryo-EM structure of human Mre11-Rad50-Nbs1 (MRN) complex bound to DNA and telomeric factor TRF2
Cryo-EM Tomogram of JCVI-Syn3A cell grown on FBS with a normal phenotype
Cryo-EM tomogram of JCVI-Syn3A cells grown on POPC + Cholesterol diet displaying an Internal Membrane phenotype
Cryo-EM tomogram of JCVI-Syn3A cells grown on a defined lipid diets
Cryo-EM image of a JCVI-Syn3A cell fed on a POPC + Cholesterol diet with a Normal phenotype
Chromosomal Passenger Complex in complex with H3T3ph Nucleosome (Class0)
Insulin receptor bound with de novo designed agonist called "S2-F1-S1"
Insulin receptor bound with de novo designed agonist called "RF-405".
Chromosomal Passenger Complex in complex with H3T3ph Nucleosome (Double Occupancy map)
Chromosomal Passenger Complex in complex with H3T3ph Nucleosome (Double Occupancy)
Chromosomal Passenger Complex in complex with H3T3ph Nucleosome (Class1)
Insulin receptor in complex with both insulin and de novo designed site-2 binder "S2B".
Cryo-EM structure of the endogenous ClpP1/ClpP2 heterocomplex from Pseudomonas aeruginosa bound to the AAA+ ClpX unfoldase.
BG505-DS SOSIP in complex with 007 bNAb Fabs - Class 2 (2 Fabs bound)
BG505-DS SOSIP in complex with 007 bNAb Fabs - Class 3 (3 Fabs bound)
Structure of Fab HB420 in complex with influenza H3N2 A/Moscow/10/1999 neuraminidase
BG505-DS SOSIP in complex with 007 bNAb Fabs - Class 1 (1 Fab bound)
CryoEM structure of decameric COMMD-like protein MBK5214510 from Flavobacteriaceae bacterium
Cryo-EM structure of octameric COMMD-like protein MBK5214510 from Flavobacteriaceae bacterium
Consensus map of ternary PROTAC-mediated complex of BRD4-BD1/CRBN/DDB1 and JQ1-AcQ bifunctional degrader
Cryo-EM structure of SARS CoV-2 RdRp S759A mutant in complex with 20-40mer RNA incorporating remdesivir
Ternary PROTAC-mediated complex of BRD4-BD1/CRBN/DDB1 and JQ1-AcQ bifunctional degrader
Cryo-EM structure of Chikungunya virus in complex with Fab fragment of neutralizing antibody IM-CKV063
Cryo-EM structure of SARS CoV-2 RdRp S759A mutant in complex with 20-40mer RNA incorporating ATP
Cryo-EM structure of SARS CoV-2 RdRp wild-type in complex with 20-40mer RNA incorporating ATP
Focus map of ternary PROTAC-mediated complex of BRD4-BD1/CRBN/DDB1 and JQ1-AcQ bifunctional degrader
Cryo-EM structure of Chikungunya virus in complex with Fab fragment of neutralizing antibody C9
Cryo-EM structure of SARS CoV-2 RdRp wild-type in complex with 20-40mer RNA incorporating Remdesivir
De novo calcium channel heptamer, CalC6_3 with DHR extensions. Off target multimerization state
Cryo-EM structure of Drosophila melanogaster insulin receptor (dmIR) bound with two DILP1, symmetric conformation
Cryo-EM structure of Drosophila melanogaster insulin receptor (dmIR) bound with one DILP2, asymmetric conformation
Cryo-EM structure of Drosophila melanogaster insulin receptor (dmIR) bound with three DILP5, asymmetric conformation
Cryo-EM structure of Drosophila melanogaster insulin receptor (dmIR) bound with one DILP1, asymmetric conformation
cryo-EM structure of full-length and internally HIS-tagged yeast E3 ubiquitin ligase Tom1p, in a closed-conformation state with helical repeat solenoid architecture
E3 ubiquitin ligase HUWE1 homolog Tom1p in closed-conformation with internal Acidic Domain deletion.
Full-length and internally HIS-tagged yeast E3 ubiquitin ligase Tom1p in an open-conformation
SARS-COV-2-6P-MUT7 S PROTEIN-DY-III-281 complex closed conformation
SARS-COV-2-6P-MUT7 S PROTEIN-DY-III-281 complex 1 RBD up conformation
wild-type bovine ABCC1 under an active turnover conformation with unhydrolyzed ATP bound and hydrolyzed ADP released
Cryo_EM density map of human FAN1 in complex with CAG-2 loop DNA substrate and PCNA
De Novo Mycobacterium tuberculosis transcription initiation promoter complex with 7-mer RNA and disordered Beta' Lid element (RNA Polymerase with Sigma-A, CarD, and RbpA)
Off-pathway Mycobacterium tuberculosis transcription initiation promoter complex (RNA Polymerase with Sigma-A, CarD, and RbpA)
De Novo Mycobacterium tuberculosis transcription initiation promoter complex with 5-mer RNA and open Beta' clamp (RNA Polymerase with Sigma-A, CarD, and RbpA)
De Novo Mycobacterium tuberculosis transcription initiation promoter complex with 6-mer RNA and closed Beta' clamp (RNA Polymerase with Sigma-A, CarD, and RbpA)
De novo backtracked transcription elongation complex of Mycobacterium tuberculosis RNA polymerase on a linear DNA fragment (TEC-Backtracked)
De Novo Mycobacterium tuberculosis transcription initiation promoter complex with 6-mer RNA and disordered Sigma-A region 4 domain (RNA Polymerase with Sigma-A, CarD, and RbpA)
De Novo Mycobacterium tuberculosis transcription initiation pre-RPO promoter complex with open Beta' clamp (RNA Polymerase with Sigma-A, CarD, and RbpA)
Cryo-EM structure of PI3Kalpha in complex with compound UCL-TRO-1938
Half barrel Pre-pore state of Y194A Vibrio cholerae cytolysin mutant in liposome.
Cryo-EM structure of PI3Kalpha H1047R in complex with compound UCL-TRO-1938
Pre-pore octameric state of T201A Vibrio cholerae cytolysin mutant in liposome
Pre-pore state (without transmembrane barrel) of Y194A Vibrio cholerae cytolysin mutant in liposome.
Cryo-EM structure of the mouse kinesin-2 tail in complex with KAP3 adaptor
Cryo-EM structure of the kinesin-2 tail domain in complex with KAP3 and APC
Structure of 70S ribosome-EF-G(P610L)-GDP-Pi-apramycin complex with tRNAs in hybrid state 1 (H1- EF-G(P610L)-GDP-Pi)
Structure of 70S ribosome-apramycin complex with tRNAs in classic state (C)
Structure of 70S ribosome-apramycin complex with tRNAs in hybrid state 1 (H1)
Structure of 70S ribosome-apramycin complex with tRNAs in hybrid state 2 (H2)
Cryo EM structure of KCa3.1_R355K_II/calmodulin channel in complex with rimtuzalcap
Amyloid fibril from the antimicrobial peptide citropin 1-3 - Polymorph Nr.1
Salmonella enterica Lamassu LmuACB in nuclease sequestration state
Amyloid fibril from the antimicrobial peptide citropin 1-3 - Polymorph Nr.3
Amyloid fibril from the antimicrobial peptide citropin 1-3 - Polymorph Nr.2L
Amyloid fibril from the antimicrobial peptide citropin 1-3 - Polymorph Nr.1L
Amyloid fibril from the antimicrobial peptide citropin 1-3 - Polymorph Nr.2
Salmonella enterica Lamassu LmuA nuclease tetramer bound to DNA duplex
Amyloid fibril from the antimicrobial peptide citropin 1-3 - Polymorph Nr.3L
Cryo-EM structure of ternary complex Ikaros-ZF2:CC-885:CRBN:DDB1 (molecular glue degrader)
Y20S (Sec18-Sec17-Sec9-Sso1-Snc1) EDTA - All Merge (Class 9, focused on D1/D2)
The complex structure of Escherichia coli AdhE (compact conformation)
Cryo-EM structure of the Dinoroseobacter shibae RC-LH1 supercomplex with incomplete LH1 ring(State 2)
Cryo-EM structure of the Dinoroseobacter shibae RC-LH1 supercomplex with incomplete LH1 ring(State 1)
Cryo-EM structure of the Dinoroseobacter shibae RC-LH1 supercomplex
Cryo-EM structure of Na+,K+-ATPase that forms a cation channel with palytoxin (ADP form)
Cryo-EM structure of Na+,K+-ATPase that forms a cation channel with palytoxin (ATP form)
Cryo-EM structure of palytoxin-bound Na+,K+-ATPase in the E2P state
Cryo-EM structure of palytoxin-bound Na+,K+-ATPase in the transient state of dephosphorylation (E2~P)
Cryo-EM Structure of EfPiwi-piRNA-target (25-nt) in the presence of EmGTSF1Q22A/R25A/K32A/K35A
Cryo-EM Structure of EfPiwi-piRNA-target (25-nt) in the presence of EmGTSF1W100A/W109A
Structure of motor1 of isw1-nucleosome double-bound complex in ADP-ADP+ state
1.5A Apoferritin imaged on 200kV Glacios with Cold-FEG and Falcon 4i
Cryo-EM tomogram of JCVi-Syn3A cell on FBS diet displaying Intercellular Tubule phenotype.
Structure of Trypanosoma cruzi Prolyl Oligopeptidase in the close state