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Neuronal FAM171A2 mediates α-synuclein fibril uptake and drives Parkinson's disease.

Wu KM, Xu QH, Liu YQ, Feng YW, Han SD, Zhang YR, Chen SD, Guo Y, Wu BS, Ma LZ, Zhang Y, Chen YL, Yang L, Yang ZF, Xiao YJ, Wang TT, Zhao J, Chen SF, Cui M, Lu BX, Le WD, Shu YS, Ye K, Li JY, Li WS, Wang J, Liu C, Yuan P, Yu JT. Wu KM, et al. Among authors: yang l. Science. 2025 Feb 21;387(6736):892-900. doi: 10.1126/science.adp3645. Epub 2025 Feb 20. Science. 2025. PMID: 39977508

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The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial.

Ma L, Hu X, Song L, Chen X, Ouyang M, Billot L, Li Q, Malavera A, Li X, Muñoz-Venturelli P, de Silva A, Thang NH, Wahab KW, Pandian JD, Wasay M, Pontes-Neto OM, Abanto C, Arauz A, Shi H, Tang G, Zhu S, She X, Liu L, Sakamoto Y, You S, Han Q, Crutzen B, Cheung E, Li Y, Wang X, Chen C, Liu F, Zhao Y, Li H, Liu Y, Jiang Y, Chen L, Wu B, Liu M, Xu J, You C, Anderson CS; INTERACT3 Investigators. Ma L, et al. Lancet. 2023 Jul 1;402(10395):27-40. doi: 10.1016/S0140-6736(23)00806-1. Epub 2023 May 25. Lancet. 2023. PMID: 37245517 Free PMC article. Clinical Trial.

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Identifying modifiable factors and their joint effect on dementia risk in the UK Biobank.

Zhang Y, Chen SD, Deng YT, You J, He XY, Wu XR, Wu BS, Yang L, Zhang YR, Kuo K, Feng JF, Cheng W, Suckling J, David Smith A, Yu JT. Zhang Y, et al. Among authors: yang l. Nat Hum Behav. 2023 Jul;7(7):1185-1195. doi: 10.1038/s41562-023-01585-x. Epub 2023 Apr 6. Nat Hum Behav. 2023. PMID: 37024724

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, … See abstract for full author list ➔ Klionsky DJ, et al. Among authors: liu y, yang l. Autophagy. 2016;12(1):1-222. doi: 10.1080/15548627.2015.1100356. Autophagy. 2016. PMID: 26799652 Free PMC article. No abstract available.

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Stigma receptors control intraspecies and interspecies barriers in Brassicaceae.

Huang J, Yang L, Yang L, Wu X, Cui X, Zhang L, Hui J, Zhao Y, Yang H, Liu S, Xu Q, Pang M, Guo X, Cao Y, Chen Y, Ren X, Lv J, Yu J, Ding J, Xu G, Wang N, Wei X, Lin Q, Yuan Y, Zhang X, Ma C, Dai C, Wang P, Wang Y, Cheng F, Zeng W, Palanivelu R, Wu HM, Zhang X, Cheung AY, Duan Q. Huang J, et al. Among authors: yang l. Nature. 2023 Feb;614(7947):303-308. doi: 10.1038/s41586-022-05640-x. Epub 2023 Jan 25. Nature. 2023. PMID: 36697825 Free PMC article.

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The X-Age Project to construct a Chinese aging clock.

Li J, Jiang M, Wang Q, Zheng Z, Shen J, Li J, Xiong M, Zheng Y, Lu X, Cai Y, Fan Y, Geng L, Ji Q, Peng Q, Sun S, Wang Y, Xin Z, Yan K, Yang Y, Yu J, Yan H, Ai D, Bai Y, Bi Y, Bian XW, Bu P, Cai JP, Cao CM, Cao F, Cao Z, Chai R, Chan P, Chen C, Chen CS, Chen C, Chen D, Chen HZ, Chen L, Chen Q, Chen X, Chen X, Chen Y, Chen ZJ, Ci W, Dai Z, Ding Q, Dong B, Dong J, Fan JG, Feng S, Feng X, Feng Y, Fu X, Fu X, Gao F, Gao J, Gao Q, Gao S, Gu Y, Guan Y, Guo F, Han JJ, Hao H, Hao J, He F, He J, He M, He M, He Q, He Z, He Z, Hong H, Hong J, Hou S, Hu C, Hu P, Hu Z, Huang C, Huang J, Huang K, Huang P, Ji X, Ji Y, Jia S, Jiang H, Jiang W, Jin L, Jin ZB, Ju S, Ju Z, Kong QP, Kong W, Kong WJ, Kong X, Lei G, Li GL, Li J, Li J, Li M, Li R, Li W, Li W, Li XJ, Li X, Liang Q, Liang Z, Lin H, Liu B, Liu CY, Liu C, Liu F, Liu J, Liu JP, Liu K, Liu L, Liu P, Liu Q, Liu Q, Liu T, Liu W, Liu X, Liu Y, Liu Y, Liu Y, Liu Y, Liu Z, Long X, Lu Y, Luo J, Luo X, Ma C, Ma S, Ma X, Mao J, Mao Z, Ng SC, Nie G, Niu Y, Peng Y, Pu J, Qi J, Qiang L, Qiao J, Qin Y, Qu A, Qu J, Ren J, Ren R, Ruan XZ, Shi A, Shi H, Shi J, So KF, Song M, Song W, Songyang Z, Su J, Sun A, Sun L, Sun Q, Sun YE, Sun Y, Tang P, Tang QQ, Tang … See abstract for full author list ➔ Li J, et al. Among authors: yang l. Nat Aging. 2025 Sep;5(9):1669-1685. doi: 10.1038/s43587-025-00935-w. Epub 2025 Sep 9. Nat Aging. 2025. PMID: 40926127 Review.

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Hepatocyte metabolic adaptations during pregnancy and lactation.

Yang L, Zhang Y, Yu XX, Zhou YH, He S, Yang L, Mao TY, Yang JG, Wu Y, Zheng QQ, Li XK, Chen HZ, Xu CR. Yang L, et al. Cell. 2025 Aug 25:S0092-8674(25)00921-3. doi: 10.1016/j.cell.2025.08.007. Online ahead of print. Cell. 2025. PMID: 40882627

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Depression, Depression Treatments, and Risk of Incident Dementia: A Prospective Cohort Study of 354,313 Participants.

Yang L, Deng YT, Leng Y, Ou YN, Li YZ, Chen SD, He XY, Wu BS, Huang SY, Zhang YR, Kuo K, Feng W, Dong Q, Feng JF, Suckling J, Smith AD, Li F, Cheng W, Yu JT. Yang L, et al. Biol Psychiatry. 2023 May 1;93(9):802-809. doi: 10.1016/j.biopsych.2022.08.026. Epub 2022 Sep 5. Biol Psychiatry. 2023. PMID: 36526487

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Psychedelic control of neuroimmune interactions governing fear.

Chung EN, Lee J, Polonio CM, Choi J, Akl CF, Kilian M, Weiß WM, Gunner G, Ye M, Heo TH, Drake SS, Yang L, d'Eca CRGL, Lee JH, Deng L, Farrenkopf D, Schüle AM, Lee HG, Afolabi O, Ghaznavi S, Smirnakis SM, Chiu IM, Kuchroo VK, Quintana FJ, Wheeler MA. Chung EN, et al. Among authors: yang l. Nature. 2025 May;641(8065):1276-1286. doi: 10.1038/s41586-025-08880-9. Epub 2025 Apr 23. Nature. 2025. PMID: 40269152

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Early detection of multiple cancer types using multidimensional cell-free DNA fragmentomics.

Bao H, Yang S, Chen X, Dong G, Mao Y, Wu S, Cheng X, Wu X, Tang W, Wu M, Tang S, Liang W, Wang Z, Yang L, Liu J, Wang T, Zhang B, Jiang K, Xu Q, Chen J, Huang H, Peng J, Xia X, Wu Y, Xu S, Tao J, Chong L, Zhu D, Yang R, Chang S, He P, Xu X, Zhang J, Shen Y, Jiang Y, Liu S, Zhang X, Wu X, Wang X, Shao Y. Bao H, et al. Among authors: yang l. Nat Med. 2025 Aug;31(8):2737-2745. doi: 10.1038/s41591-025-03735-2. Epub 2025 May 27. Nat Med. 2025. PMID: 40425843

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