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Large language models encode clinical knowledge.

Singhal K, Azizi S, Tu T, Mahdavi SS, Wei J, Chung HW, Scales N, Tanwani A, Cole-Lewis H, Pfohl S, Payne P, Seneviratne M, Gamble P, Kelly C, Babiker A, Schärli N, Chowdhery A, Mansfield P, Demner-Fushman D, Agüera Y Arcas B, Webster D, Corrado GS, Matias Y, Chou K, Gottweis J, Tomasev N, Liu Y, Rajkomar A, Barral J, Semturs C, Karthikesalingam A, Natarajan V. Singhal K, et al. Among authors: tu t. Nature. 2023 Aug;620(7972):172-180. doi: 10.1038/s41586-023-06291-2. Epub 2023 Jul 12. Nature. 2023. PMID: 37438534 Free PMC article.

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Metformin suppresses vascular smooth muscle cell senescence by promoting autophagic flux.

Tai S, Sun J, Zhou Y, Zhu Z, He Y, Chen M, Yang H, Xiao Y, Tu T, Tang L, Li X, Zeng J, Zheng X, Zhou S. Tai S, et al. Among authors: tu t. J Adv Res. 2022 Nov;41:205-218. doi: 10.1016/j.jare.2021.12.009. Epub 2021 Dec 22. J Adv Res. 2022. PMID: 36328749 Free PMC article.

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Towards conversational diagnostic artificial intelligence.

Tu T, Schaekermann M, Palepu A, Saab K, Freyberg J, Tanno R, Wang A, Li B, Amin M, Cheng Y, Vedadi E, Tomasev N, Azizi S, Singhal K, Hou L, Webson A, Kulkarni K, Mahdavi SS, Semturs C, Gottweis J, Barral J, Chou K, Corrado GS, Matias Y, Karthikesalingam A, Natarajan V. Tu T, et al. Nature. 2025 Jun;642(8067):442-450. doi: 10.1038/s41586-025-08866-7. Epub 2025 Apr 9. Nature. 2025. PMID: 40205050 Free PMC article. Clinical Trial.

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The triglyceride-glucose index and its obesity-related derivatives as predictors of all-cause and cardiovascular mortality in hypertensive patients: insights from NHANES data with machine learning analysis.

Li C, Zhang Z, Luo X, Xiao Y, Tu T, Liu C, Liu Q, Wang C, Dai Y, Zhang Z, Zheng C, Lin J. Li C, et al. Among authors: tu t. Cardiovasc Diabetol. 2025 Jan 29;24(1):47. doi: 10.1186/s12933-025-02591-1. Cardiovasc Diabetol. 2025. PMID: 39881352 Free PMC article.

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Toward expert-level medical question answering with large language models.

Singhal K, Tu T, Gottweis J, Sayres R, Wulczyn E, Amin M, Hou L, Clark K, Pfohl SR, Cole-Lewis H, Neal D, Rashid QM, Schaekermann M, Wang A, Dash D, Chen JH, Shah NH, Lachgar S, Mansfield PA, Prakash S, Green B, Dominowska E, Agüera Y Arcas B, Tomašev N, Liu Y, Wong R, Semturs C, Mahdavi SS, Barral JK, Webster DR, Corrado GS, Matias Y, Azizi S, Karthikesalingam A, Natarajan V. Singhal K, et al. Among authors: tu t. Nat Med. 2025 Mar;31(3):943-950. doi: 10.1038/s41591-024-03423-7. Epub 2025 Jan 8. Nat Med. 2025. PMID: 39779926 Free PMC article.

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Association between the Life's Essential 8 Health Behaviors and Prognosis in Patients with Advanced Cardiovascular-Kidney-Metabolic Syndrome.

Tan S, Zhou J, Li F, Zeng G, Liu N, Tu T, Chen H, Lin Q, Liu Q. Tan S, et al. Among authors: tu t. Eur J Prev Cardiol. 2025 Jul 17:zwaf443. doi: 10.1093/eurjpc/zwaf443. Online ahead of print. Eur J Prev Cardiol. 2025. PMID: 40674721

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Identification and validation of aging-related genes in atrial fibrillation.

Zhou Y, Sun C, Ma Y, Huang Y, Wu K, Huang S, Lin Q, Zhu J, Ning Z, Liu N, Tu T, Liu Q. Zhou Y, et al. Among authors: tu t. PLoS One. 2023 Nov 13;18(11):e0294282. doi: 10.1371/journal.pone.0294282. eCollection 2023. PLoS One. 2023. PMID: 37956134 Free PMC article.

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A Review on Bacteriorhodopsin-Based Bioelectronic Devices.

Li YT, Tian Y, Tian H, Tu T, Gou GY, Wang Q, Qiao YC, Yang Y, Ren TL. Li YT, et al. Among authors: tu t. Sensors (Basel). 2018 Apr 27;18(5):1368. doi: 10.3390/s18051368. Sensors (Basel). 2018. PMID: 29702621 Free PMC article. Review.

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GTS-21 alleviates sepsis-induced atrial fibrillation susceptibility by modulating macrophage polarization and Neuregulin-1 secretion.

Zhou J, Wu K, Ma Y, Zhu J, Zhou Y, Zhang Z, Li F, Zeng G, Li S, Tan S, Zhang Y, Wan C, Tu T, Lin Q, Liu Q. Zhou J, et al. Among authors: tu t. Int Immunopharmacol. 2025 May 8;154:114561. doi: 10.1016/j.intimp.2025.114561. Epub 2025 Apr 5. Int Immunopharmacol. 2025. PMID: 40186903 Free article.

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Amino acid profile alteration in age-related atrial fibrillation.

Huang Y, Lin Q, Zhou Y, Zhu J, Ma Y, Wu K, Ning Z, Zhang Z, Liu N, Li M, Liu Y, Tu T, Liu Q. Huang Y, et al. Among authors: tu t. J Transl Med. 2024 Mar 9;22(1):259. doi: 10.1186/s12967-024-05028-7. J Transl Med. 2024. PMID: 38461346 Free PMC article.

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