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Androgen conspires with the CD8⁺ T cell exhaustion program and contributes to sex bias in cancer.

Kwon H, Schafer JM, Song NJ, Kaneko S, Li A, Xiao T, Ma A, Allen C, Das K, Zhou L, Riesenberg B, Chang Y, Weltge P, Velegraki M, Oh DY, Fong L, Ma Q, Sundi D, Chung D, Li X, Li Z. Kwon H, et al. Among authors: song nj. Sci Immunol. 2022 Jul;7(73):eabq2630. doi: 10.1126/sciimmunol.abq2630. Epub 2022 Jul 1. Sci Immunol. 2022. PMID: 35420889 Free PMC article.

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Spatial and functional targeting of intratumoral Tregs reverses CD8+ T cell exhaustion and promotes cancer immunotherapy.

Zhou L, Velegraki M, Wang Y, Mandula JK, Chang Y, Liu W, Song NJ, Kwon H, Xiao T, Bolyard C, Hong F, Xin G, Ma Q, Rubinstein MP, Wen H, Li Z. Zhou L, et al. Among authors: song nj. J Clin Invest. 2024 May 23;134(14):e180080. doi: 10.1172/JCI180080. J Clin Invest. 2024. PMID: 38787791 Free PMC article.

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Cytotoxic NK Cells Impede Response to Checkpoint Immunotherapy in Melanoma with an Immune-Excluded Phenotype.

Pozniak J, Roda N, Landeloos E, Antoranz A, Van Herck Y, De Visscher A, Demaerel PG, Vanwynsberghe L, Declercq J, Gkemisis C, Bervoets G, Song NJ, Bassez A, Browaeys R, Pollaris L, Bosisio FM, Boecxstaens V, Saeys Y, Lambrechts D, Li Z, Matthys P, Bechter O, Marine JC. Pozniak J, et al. Among authors: song nj. Cancer Discov. 2025 Sep 4;15(9):1819-1834. doi: 10.1158/2159-8290.CD-24-1208. Cancer Discov. 2025. PMID: 40530504 Free PMC article.

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Tumor-associated NK Cells Regulate Distinct CD8+ T-cell Differentiation Program in Cancer and Contribute to Resistance against Immune Checkpoint Blockers.

Song NJ, Xie J, Jung KJ, Wang Y, Pozniak J, Roda N, Marine JC, Riesenberg BP, Jeon H, Ma A, Cox N, Wethington D, Reynolds K, Xiao T, Li A, Kronen P, Denko N, Carbone DP, Ma Q, Carson WE 3rd, Mundy-Bosse BL, Burd CE, Das J, Chung D, Li Z. Song NJ, et al. Cancer Discov. 2025 Sep 4;15(9):1835-1857. doi: 10.1158/2159-8290.CD-24-1232. Cancer Discov. 2025. PMID: 40530506

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Postinfusion PD-1+ CD8+ CAR T cells identify patients responsive to CD19 CAR T-cell therapy in non-Hodgkin lymphoma.

Denlinger N, Song NJ, Zhang X, Jeon H, Peterson C, Wang Y, Reynolds K, Bolz RM, Miao J, Song C, Wu D, Chan WK, Bezerra E, Epperla N, Voorhees TJ, Brammer J, Kittai AS, Bond DA, Sawalha Y, Sigmund A, Reneau JC, Rubinstein MP, Hanel W, Christian B, Baiocchi RA, Maddocks K, Alinari L, Vasu S, de Lima M, Chung D, Jaglowski S, Li Z, Huang X, Yang Y. Denlinger N, et al. Among authors: song nj. Blood Adv. 2024 Jun 25;8(12):3140-3153. doi: 10.1182/bloodadvances.2023012073. Blood Adv. 2024. PMID: 38607381 Free PMC article.

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Selective targeting of GARP-LTGFβ axis in the tumor microenvironment augments PD-1 blockade via enhancing CD8⁺ T cell antitumor immunity.

Li A, Chang Y, Song NJ, Wu X, Chung D, Riesenberg BP, Velegraki M, Giuliani GD, Das K, Okimoto T, Kwon H, Chakravarthy KB, Bolyard C, Wang Y, He K, Gatti-Mays M, Das J, Yang Y, Gewirth DT, Ma Q, Carbone D, Li Z. Li A, et al. Among authors: song nj. J Immunother Cancer. 2022 Sep;10(9):e005433. doi: 10.1136/jitc-2022-005433. J Immunother Cancer. 2022. PMID: 36096533 Free PMC article.

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Mechanisms underlying UCP1 dependent and independent adipocyte thermogenesis.

Chang SH, Song NJ, Choi JH, Yun UJ, Park KW. Chang SH, et al. Among authors: song nj. Obes Rev. 2019 Feb;20(2):241-251. doi: 10.1111/obr.12796. Epub 2018 Nov 18. Obes Rev. 2019. PMID: 30450758 Review.

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Development of molecular and pharmacological switches for chimeric antigen receptor T cells.

Wu BX, Song NJ, Riesenberg BP, Li Z. Wu BX, et al. Among authors: song nj. Exp Hematol Oncol. 2019 Nov 5;8:27. doi: 10.1186/s40164-019-0151-z. eCollection 2019. Exp Hematol Oncol. 2019. PMID: 31709128 Free PMC article.

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Induction of thermogenic adipocytes: molecular targets and thermogenic small molecules.

Song NJ, Chang SH, Li DY, Villanueva CJ, Park KW. Song NJ, et al. Exp Mol Med. 2017 Jul 7;49(7):e353. doi: 10.1038/emm.2017.70. Exp Mol Med. 2017. PMID: 28684864 Free PMC article. Review.

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Rapid assay development for low input targeted proteomics using a versatile linear ion trap.

Shannon AE, Teodorescu RN, Song NJ, Heil LR, Jacob CC, Remes PM, Li Z, Rubinstein MP, Searle BC. Shannon AE, et al. Among authors: song nj. Nat Commun. 2025 Apr 23;16(1):3794. doi: 10.1038/s41467-025-58757-8. Nat Commun. 2025. PMID: 40263265 Free PMC article.

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