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The role of brain vasculature in neurodegenerative disorders.

Sweeney MD, Kisler K, Montagne A, Toga AW, Zlokovic BV. Sweeney MD, et al. Among authors: kisler k. Nat Neurosci. 2018 Oct;21(10):1318-1331. doi: 10.1038/s41593-018-0234-x. Epub 2018 Sep 24. Nat Neurosci. 2018. PMID: 30250261 Free PMC article. Review.

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Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease.

Kisler K, Nelson AR, Montagne A, Zlokovic BV. Kisler K, et al. Nat Rev Neurosci. 2017 Jul;18(7):419-434. doi: 10.1038/nrn.2017.48. Epub 2017 May 18. Nat Rev Neurosci. 2017. PMID: 28515434 Free PMC article. Review.

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Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.

Shi Y, Lin S, Staats KA, Li Y, Chang WH, Hung ST, Hendricks E, Linares GR, Wang Y, Son EY, Wen X, Kisler K, Wilkinson B, Menendez L, Sugawara T, Woolwine P, Huang M, Cowan MJ, Ge B, Koutsodendris N, Sandor KP, Komberg J, Vangoor VR, Senthilkumar K, Hennes V, Seah C, Nelson AR, Cheng TY, Lee SJ, August PR, Chen JA, Wisniewski N, Hanson-Smith V, Belgard TG, Zhang A, Coba M, Grunseich C, Ward ME, van den Berg LH, Pasterkamp RJ, Trotti D, Zlokovic BV, Ichida JK. Shi Y, et al. Among authors: kisler k. Nat Med. 2018 Mar;24(3):313-325. doi: 10.1038/nm.4490. Epub 2018 Feb 5. Nat Med. 2018. PMID: 29400714 Free PMC article.

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Blood-brain barrier link to human cognitive impairment and Alzheimer's Disease.

Barisano G, Montagne A, Kisler K, Schneider JA, Wardlaw JM, Zlokovic BV. Barisano G, et al. Among authors: kisler k. Nat Cardiovasc Res. 2022 Feb;1(2):108-115. doi: 10.1038/s44161-021-00014-4. Epub 2022 Feb 7. Nat Cardiovasc Res. 2022. PMID: 35450117 Free PMC article.

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Anti-malaria drug artesunate prevents development of amyloid-β pathology in mice by upregulating PICALM at the blood-brain barrier.

Kisler K, Sagare AP, Lazic D, Bazzi S, Lawson E, Hsu CJ, Wang Y, Ramanathan A, Nelson AR, Zhao Z, Zlokovic BV. Kisler K, et al. Mol Neurodegener. 2023 Jan 27;18(1):7. doi: 10.1186/s13024-023-00597-5. Mol Neurodegener. 2023. PMID: 36707892 Free PMC article.

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The blood-brain barrier: a help and a hindrance.

Rust R, Yin H, Achón Buil B, Sagare AP, Kisler K. Rust R, et al. Among authors: kisler k. Brain. 2025 Jul 7;148(7):2262-2282. doi: 10.1093/brain/awaf068. Brain. 2025. PMID: 39969549 Free PMC article. Review.

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How the brain regulates its own immune system.

Kisler K, Zlokovic BV. Kisler K, et al. Nat Neurosci. 2022 May;25(5):532-534. doi: 10.1038/s41593-022-01066-w. Nat Neurosci. 2022. PMID: 35501381 No abstract available.

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A molecular brain atlas reveals cellular shifts during the repair phase of stroke.

Weber RZ, Buil BA, Rentsch NH, Bosworth A, Zhang M, Kisler K, Tackenberg C, Zlokovic BV, Rust R. Weber RZ, et al. Among authors: kisler k. bioRxiv [Preprint]. 2024 Aug 22:2024.08.21.608971. doi: 10.1101/2024.08.21.608971. bioRxiv. 2024. Update in: J Neuroinflammation. 2025 Apr 18;22(1):112. doi: 10.1186/s12974-025-03437-z. PMID: 39229128 Free PMC article. Updated. Preprint.

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Microglia have a grip on brain microvasculature.

Kisler K, Nikolakopoulou AM, Zlokovic BV. Kisler K, et al. Nat Commun. 2021 Sep 6;12(1):5290. doi: 10.1038/s41467-021-25595-3. Nat Commun. 2021. PMID: 34489417 Free PMC article.

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The blood-brain barrier as a treatment target for neurodegenerative disorders.

Rust R, Sagare AP, Zhang M, Zlokovic BV, Kisler K. Rust R, et al. Among authors: kisler k. Expert Opin Drug Deliv. 2025 May;22(5):673-692. doi: 10.1080/17425247.2025.2480654. Epub 2025 Mar 21. Expert Opin Drug Deliv. 2025. PMID: 40096820 Free article. Review.

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