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Irisin ameliorates age-associated sarcopenia and metabolic dysfunction.

Guo M, Yao J, Li J, Zhang J, Wang D, Zuo H, Zhang Y, Xu B, Zhong Y, Shen F, Lu J, Ding S, Hu C, Xu L, Xiao J, Ma X. Guo M, et al. Among authors: yao j. J Cachexia Sarcopenia Muscle. 2023 Feb;14(1):391-405. doi: 10.1002/jcsm.13141. Epub 2022 Dec 12. J Cachexia Sarcopenia Muscle. 2023. PMID: 36510115 Free PMC article.

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ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway.

Cai L, Gong Q, Qi L, Xu T, Suo Q, Li X, Wang W, Jing Y, Yang D, Xu Z, Yuan F, Tang Y, Yang G, Ding J, Chen H, Tian H. Cai L, et al. Among authors: jing y. Cell Commun Signal. 2022 Apr 23;20(1):56. doi: 10.1186/s12964-022-00862-y. Cell Commun Signal. 2022. PMID: 35461293 Free PMC article.

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AAV-Mediated nuclear localized PGC1α4 delivery in muscle ameliorates sarcopenia and aging-associated metabolic dysfunctions.

Guo M, Zhang J, Ma Y, Zhu Z, Zuo H, Yao J, Wu X, Wang D, Yu J, Meng M, Liu C, Zhang Y, Chen J, Lu J, Ding S, Hu C, Ma X, Xu L. Guo M, et al. Among authors: yao j. Aging Cell. 2023 Oct;22(10):e13961. doi: 10.1111/acel.13961. Epub 2023 Aug 16. Aging Cell. 2023. PMID: 37584432 Free PMC article.

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The role of inflammasomes in human diseases and their potential as therapeutic targets.

Yao J, Sterling K, Wang Z, Zhang Y, Song W. Yao J, et al. Signal Transduct Target Ther. 2024 Jan 5;9(1):10. doi: 10.1038/s41392-023-01687-y. Signal Transduct Target Ther. 2024. PMID: 38177104 Free PMC article. Review.

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Targeting NLRP3 inflammasome for neurodegenerative disorders.

Yao J, Wang Z, Song W, Zhang Y. Yao J, et al. Mol Psychiatry. 2023 Nov;28(11):4512-4527. doi: 10.1038/s41380-023-02239-0. Epub 2023 Sep 5. Mol Psychiatry. 2023. PMID: 37670126 Review.

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BMAL1/PGC1α4-FNDC5/irisin axis impacts distinct outcomes of time-of-day resistance exercise.

Guo M, Shen F, Guo X, Zhang J, Ma Y, Wu X, Zuo H, Yao J, Hu Y, Wang D, Li Y, Li J, Qiu J, Yu J, Meng M, Zheng Y, Chen X, Gong M, Liu K, Jin L, Ren X, Zhang Q, Zhao Y, Gu X, Shen F, Li D, Gao L, Liu C, Zhou F, Li M, Wang J, Ding S, Ma X, Lu J, Xie C, Xiao J, Xu L. Guo M, et al. Among authors: yao j. J Sport Health Sci. 2024 Aug 24;14:100968. doi: 10.1016/j.jshs.2024.100968. Online ahead of print. J Sport Health Sci. 2024. PMID: 39187065 Free PMC article.

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Viral infection and spread are inhibited by the polyubiquitination and downregulation of TRPV2 channel by the interferon-stimulated gene TRIM21.

Guo YY, Gao Y, Zhao YL, Xie C, Gan H, Cheng X, Yang LP, Hu J, Shu HB, Zhong B, Lin D, Yao J. Guo YY, et al. Among authors: yao j. Cell Rep. 2024 Apr 23;43(4):114095. doi: 10.1016/j.celrep.2024.114095. Epub 2024 Apr 12. Cell Rep. 2024. PMID: 38613787 Free article.

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Palmitoylation by ZDHHC4 inhibits TRPV1-mediated nociception.

Zhang Y, Zhang M, Tang C, Hu J, Cheng X, Li Y, Chen Z, Yin Y, Xie C, Li D, Yao J. Zhang Y, et al. Among authors: yao j. EMBO Rep. 2025 Jan;26(1):101-121. doi: 10.1038/s44319-024-00317-0. Epub 2024 Nov 11. EMBO Rep. 2025. PMID: 39528731 Free PMC article.

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Single-cell transcriptomic and cross-species comparison analyses reveal distinct molecular changes of porcine testes during puberty.

Wang X, Wang Y, Wang Y, Guo Y, Zong R, Hu S, Yue J, Yao J, Han C, Guo J, Zhao J. Wang X, et al. Among authors: yao j. Commun Biol. 2024 Nov 9;7(1):1478. doi: 10.1038/s42003-024-07163-9. Commun Biol. 2024. PMID: 39521938 Free PMC article.

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Inhibiting phosphatase and actin regulator 1 expression is neuroprotective in the context of traumatic brain injury.

Jing Y, Zhang L, Chen SW, Guo Y, Ju SM, Yuan F, Chen H, Yang DX, Tian HL, Xu ZM, Ding J. Jing Y, et al. Neural Regen Res. 2023 Jul;18(7):1578-1583. doi: 10.4103/1673-5374.357904. Neural Regen Res. 2023. PMID: 36571365 Free PMC article.

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