Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1978 1
1984 1
1985 1
1986 1
1996 1
2000 1
2003 1
2007 2
2008 2
2010 1
2014 1
2020 1
2022 2
2023 1
2024 3
2025 3

Search Results

21 results

Results by year

Filters applied: . Clear all
Your search was processed without automatic term mapping because it retrieved zero results.
Page 1
Identification of aceNKPs, a committed common progenitor population of the ILC1 and NK cell continuum.
Rodriguez-Rodriguez N, Clark PA, Gogoi M, Ferreira ACF, Kerscher B, Crisp A, Jolin HE, Murphy JE, Sivasubramaniam M, Pedro L, Walker JA, Heycock MWD, Shields JD, Barlow JL, McKenzie ANJ. Rodriguez-Rodriguez N, et al. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2203454119. doi: 10.1073/pnas.2203454119. Epub 2022 Nov 29. Proc Natl Acad Sci U S A. 2022. PMID: 36442116 Free PMC article.
These common ILC1/NK cell progenitors (ILC1/NKP), which we call "aceNKPs", are defined as lineage(-)Id2(+)IL-7Ralpha(+)CD25(-)alpha4beta7(-)NKG2A/C/E(+)Bcl11b(-). In vitro, aceNKPs differentiate into group 1 ILCs, including NK-like cells that express Eomes without the requ …
These common ILC1/NK cell progenitors (ILC1/NKP), which we call "aceNKPs", are defined as lineage(-)Id2(+)IL-7Ralpha(+)CD25(-)alpha4beta7(-) …
phiX174 cistron A protein is a multifunctional enzyme in DNA replication.
Eisenberg S, Griffith J, Kornberg A. Eisenberg S, et al. Proc Natl Acad Sci U S A. 1977 Aug;74(8):3198-202. doi: 10.1073/pnas.74.8.3198. Proc Natl Acad Sci U S A. 1977. PMID: 269383 Free PMC article.
G., Brown, N. L., Coulson, A. R., Fiddes, J. C., Hutchison, C. A., III, Slocomb, P. M. Y. & Smith, M. (1977) Nature 265, 687-695]. ...
G., Brown, N. L., Coulson, A. R., Fiddes, J. C., Hutchison, C. A., III, Slocomb, P. M. Y. & Smith, M. (1977) Nature …
Formation of extramembrane β-strands controls dimerization of transmembrane helices in amyloid precursor protein C99.
Pantelopulos GA, Matsuoka D, Hutchison JM, Sanders CR, Sugita Y, Straub JE, Thirumalai D. Pantelopulos GA, et al. Proc Natl Acad Sci U S A. 2022 Dec 27;119(52):e2212207119. doi: 10.1073/pnas.2212207119. Epub 2022 Dec 20. Proc Natl Acad Sci U S A. 2022. PMID: 36538482 Free PMC article.
The 99-residue C-terminal domain of amyloid precursor protein (APP-C99), precursor to amyloid beta (Abeta), is a transmembrane (TM) protein containing intrinsically disordered N- and C-terminal extramembrane domains. ...The C99 monomer has a propensity to form beta- …
The 99-residue C-terminal domain of amyloid precursor protein (APP-C99), precursor to amyloid beta (Abeta), is a transmembrane (TM) p …
Safety, Pharmacokinetics, and Pharmacodynamics of a First-in-Class ClC-1 Inhibitor to Enhance Muscle Excitability: Phase I Randomized Controlled Trial.
Ruijs TQ, de Cuba CMKE, Heuberger JAAC, Hutchison J, Bold J, Grønnebæk TS, Jensen KG, Chin E, Quiroz JA, Petersen TK, Flagstad P, de Kam ML, van Esdonk MJ, Klaassen E, Doll RJ, Koopmans IW, de Goede AA, Aulin LBS, Pedersen TH, Groeneveld GJ. Ruijs TQ, et al. Clin Pharmacol Ther. 2025 Mar;117(3):768-778. doi: 10.1002/cpt.3516. Epub 2024 Dec 9. Clin Pharmacol Ther. 2025. PMID: 39651850 Free PMC article. Clinical Trial.
Gene content phylogeny of herpesviruses.
Montague MG, Hutchison CA 3rd. Montague MG, et al. Proc Natl Acad Sci U S A. 2000 May 9;97(10):5334-9. doi: 10.1073/pnas.97.10.5334. Proc Natl Acad Sci U S A. 2000. PMID: 10805793 Free PMC article.
De novo missense variants in ZBTB47 are associated with developmental delays, hypotonia, seizures, gait abnormalities, and variable movement abnormalities.
Ward SK, Wadley A, Tsai CA, Benke PJ, Emrick L, Fisher K, Houck KM, Dai H; Undiagnosed Diseases Network; Guillen Sacoto MJ, Craigen W, Glaser K, Murdock DR, Rohena L, Diderich KEM, Bruggenwirth HT, Lee B, Bacino C, Burrage LC, Rosenfeld JA. Ward SK, et al. Am J Med Genet A. 2024 Jan;194(1):17-30. doi: 10.1002/ajmg.a.63399. Epub 2023 Sep 25. Am J Med Genet A. 2024. PMID: 37743782 Free PMC article.
All five patients are heterozygous for a de novo missense variant in ZBTB47, with p.(Glu680Gly) (c.2039A>G) detected in one patient and p.(Glu477Lys) (c.1429G>A) identified in the other four patients. ...
All five patients are heterozygous for a de novo missense variant in ZBTB47, with p.(Glu680Gly) (c.2039A>G) detected in one patien …
Rational redesign of the folding pathway of a modular protein.
Lowe AR, Itzhaki LS. Lowe AR, et al. Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2679-84. doi: 10.1073/pnas.0604653104. Epub 2007 Feb 13. Proc Natl Acad Sci U S A. 2007. PMID: 17299057 Free PMC article.
Using site-directed mutagenesis, we find that folding of wild-type myotrophin is initiated at the C-terminal repeats. However, close examination of the mutant chevron plots reveals that simple models are insufficient to describe all of the data, and double mutant analysis …
Using site-directed mutagenesis, we find that folding of wild-type myotrophin is initiated at the C-terminal repeats. However, close …
Shifting transition states in the unfolding of a large ankyrin repeat protein.
Werbeck ND, Rowling PJ, Chellamuthu VR, Itzhaki LS. Werbeck ND, et al. Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):9982-7. doi: 10.1073/pnas.0705300105. Epub 2008 Jul 16. Proc Natl Acad Sci U S A. 2008. PMID: 18632570 Free PMC article.
The data are consistent with a model in which the N-terminal half of the protein unfolds first by unraveling progressively from the start of the polypeptide chain to form an intermediate; in the next step, the C-terminal half of the protein unfolds via two pathways whose t …
The data are consistent with a model in which the N-terminal half of the protein unfolds first by unraveling progressively from the start of …
Generating a synthetic genome by whole genome assembly: phiX174 bacteriophage from synthetic oligonucleotides.
Smith HO, Hutchison CA 3rd, Pfannkoch C, Venter JC. Smith HO, et al. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15440-5. doi: 10.1073/pnas.2237126100. Epub 2003 Dec 2. Proc Natl Acad Sci U S A. 2003. PMID: 14657399 Free PMC article.
The procedure involves three key steps: (i). gel purification of pooled oligonucleotides to reduce contamination with molecules of incorrect chain length, (ii). ligation of the oligonucleotides under stringent annealing conditions (55 degrees C) to select against annealing …
The procedure involves three key steps: (i). gel purification of pooled oligonucleotides to reduce contamination with molecules of incorrect …
The Arabidopsis epigenetic regulator ICU11 as an accessory protein of Polycomb Repressive Complex 2.
Bloomer RH, Hutchison CE, Bäurle I, Walker J, Fang X, Perera P, Velanis CN, Gümüs S, Spanos C, Rappsilber J, Feng X, Goodrich J, Dean C. Bloomer RH, et al. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16660-16666. doi: 10.1073/pnas.1920621117. Epub 2020 Jun 29. Proc Natl Acad Sci U S A. 2020. PMID: 32601198 Free PMC article.
To investigate its primary molecular function we identified the Arabidopsis FLOWERING LOCUS C (FLC) as a direct target and found icu11 disrupted the cold-induced, Polycomb-mediated silencing underlying vernalization. icu11 prevented reduction in H3K36me3 levels normally se …
To investigate its primary molecular function we identified the Arabidopsis FLOWERING LOCUS C (FLC) as a direct target and found icu1 …
21 results