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A new antibiotic selectively kills Gram-negative pathogens.

Imai Y, Meyer KJ, Iinishi A, Favre-Godal Q, Green R, Manuse S, Caboni M, Mori M, Niles S, Ghiglieri M, Honrao C, Ma X, Guo JJ, Makriyannis A, Linares-Otoya L, Böhringer N, Wuisan ZG, Kaur H, Wu R, Mateus A, Typas A, Savitski MM, Espinoza JL, O'Rourke A, Nelson KE, Hiller S, Noinaj N, Schäberle TF, D'Onofrio A, Lewis K. Imai Y, et al. Among authors: d onofrio a. Nature. 2019 Dec;576(7787):459-464. doi: 10.1038/s41586-019-1791-1. Epub 2019 Nov 20. Nature. 2019. PMID: 31747680 Free PMC article.

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A selective antibiotic for Lyme disease.

Leimer N, Wu X, Imai Y, Morrissette M, Pitt N, Favre-Godal Q, Iinishi A, Jain S, Caboni M, Leus IV, Bonifay V, Niles S, Bargabos R, Ghiglieri M, Corsetti R, Krumpoch M, Fox G, Son S, Klepacki D, Polikanov YS, Freliech CA, McCarthy JE, Edmondson DG, Norris SJ, D'Onofrio A, Hu LT, Zgurskaya HI, Lewis K. Leimer N, et al. Among authors: d onofrio a. Cell. 2021 Oct 14;184(21):5405-5418.e16. doi: 10.1016/j.cell.2021.09.011. Epub 2021 Oct 6. Cell. 2021. PMID: 34619078 Free PMC article.

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Total Synthesis of Kibdelomycin.

He C, Wang Y, Bi C, Peters DS, Gallagher TJ, Teske J, Chen JS, Corsetti R, D'Onofrio A, Lewis K, Baran PS. He C, et al. Among authors: d onofrio a. Angew Chem Int Ed Engl. 2022 Aug 8;61(32):e202206183. doi: 10.1002/anie.202206183. Epub 2022 Jul 6. Angew Chem Int Ed Engl. 2022. PMID: 35704446 Free PMC article.

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Uncultured microorganisms as a source of secondary metabolites.

Lewis K, Epstein S, D'Onofrio A, Ling LL. Lewis K, et al. Among authors: d onofrio a. J Antibiot (Tokyo). 2010 Aug;63(8):468-76. doi: 10.1038/ja.2010.87. Epub 2010 Jul 21. J Antibiot (Tokyo). 2010. PMID: 20648021 Review.

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A Distinct Microbiome Signature in Posttreatment Lyme Disease Patients.

Morrissette M, Pitt N, González A, Strandwitz P, Caboni M, Rebman AW, Knight R, D'Onofrio A, Aucott JN, Soloski MJ, Lewis K. Morrissette M, et al. Among authors: d onofrio a. mBio. 2020 Sep 29;11(5):e02310-20. doi: 10.1128/mBio.02310-20. mBio. 2020. PMID: 32994327 Free PMC article.

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Author Correction: A new antibiotic selectively kills Gram-negative pathogens.

Imai Y, Meyer KJ, Iinishi A, Favre-Godal Q, Green R, Manuse S, Caboni M, Mori M, Niles S, Ghiglieri M, Honrao C, Ma X, Guo JJ, Makriyannis A, Linares-Otoya L, Böhringer N, Wuisan ZG, Kaur H, Wu R, Mateus A, Typas A, Savitski MM, Espinoza JL, O'Rourke A, Nelson KE, Hiller S, Noinaj N, Schäberle TF, D'Onofrio A, Lewis K. Imai Y, et al. Among authors: d onofrio a. Nature. 2020 Apr;580(7802):E3. doi: 10.1038/s41586-020-2063-9. Nature. 2020. PMID: 32269338

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Identifying Vancomycin as an Effective Antibiotic for Killing Borrelia burgdorferi.

Wu X, Sharma B, Niles S, O'Connor K, Schilling R, Matluck N, D'Onofrio A, Hu LT, Lewis K. Wu X, et al. Among authors: d onofrio a. Antimicrob Agents Chemother. 2018 Oct 24;62(11):e01201-18. doi: 10.1128/AAC.01201-18. Print 2018 Nov. Antimicrob Agents Chemother. 2018. PMID: 30126963 Free PMC article.

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Siderophores from neighboring organisms promote the growth of uncultured bacteria.

D'Onofrio A, Crawford JM, Stewart EJ, Witt K, Gavrish E, Epstein S, Clardy J, Lewis K. D'Onofrio A, et al. Chem Biol. 2010 Mar 26;17(3):254-64. doi: 10.1016/j.chembiol.2010.02.010. Chem Biol. 2010. PMID: 20338517 Free PMC article.

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Corrigendum to "Systematic comparisons between Lyme disease and post-treatment Lyme disease syndrome in the U.S. with administrative claims data".

Chung MK, Caboni M, Strandwitz P, D'Onofrio A, Lewis K, Patel CJ. Chung MK, et al. Among authors: d onofrio a. EBioMedicine. 2023 Jul;93:104652. doi: 10.1016/j.ebiom.2023.104652. Epub 2023 Jun 19. EBioMedicine. 2023. PMID: 37343362 Free PMC article. No abstract available.

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Systematic comparisons between Lyme disease and post-treatment Lyme disease syndrome in the U.S. with administrative claims data.

Chung MK, Caboni M, Strandwitz P, D'Onofrio A, Lewis K, Patel CJ. Chung MK, et al. Among authors: d onofrio a. EBioMedicine. 2023 Apr;90:104524. doi: 10.1016/j.ebiom.2023.104524. Epub 2023 Mar 21. EBioMedicine. 2023. PMID: 36958992 Free PMC article.

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