Nature

Gastrointestinal diseases articles from across Nature Portfolio

Gastrointestinal diseases are those that affect any section of the gastrointestinal tract, from the oesophagus to the rectum, and the accessory digestive organs liver, gall bladder and pancreas. The term encompasses acute, chronic, recurrent or functional disorders and covers a wide range of diseases, including inflammatory bowel disease and functional dyspepsia.

Related Subjects

Latest Research and Reviews

Mechanisms of orphan nuclear receptor Nur77 in liver health, disease, and therapeutic potential: narrative review
- Ola Alsharif
- Krista Rombouts
ReviewsOpen Access01 Oct 2025 npj Gut and Liver
Volume: 2, P: 24
Intermittent vs. continuous: a comparative narrative review of enteral and parenteral nutrition support strategies in the perioperative setting
- Zijun Zhou
- Jianping Zhou
ReviewsOpen Access01 Oct 2025 European Journal of Clinical Nutrition
P: 1-6
A randomized trial of inulin for bowel symptoms, depression and quality of life in constipation predominant IBS
- Çağlar Akçalı
- Aslı Uçar
- Kadri Atay
ResearchOpen Access01 Oct 2025 Scientific Reports
Volume: 15, P: 34252
Portal hypertension contributes to ascites formation via the Piezo1−nuclear factor kappa-B−aquaporin1 pathway in liver cirrhosis
- Ning Wei
- Li Du
- Yuhu Song
ResearchOpen Access01 Oct 2025 Experimental & Molecular Medicine
P: 1-12
Helicobacter pylori antimicrobial resistance and gene variants in Shandong Province
- Zhijing Xue
- Qi Zhao
- Guohai Su
ResearchOpen Access01 Oct 2025 Scientific Reports
Volume: 15, P: 34244
Assessing prevalence and risk factors for REM sleep behavior disorder among patients with inflammatory bowel disease
- Vijaya L. Reddy
- Zihan Chen
- Brian B. Koo
ResearchOpen Access01 Oct 2025 npj Parkinson's Disease
Volume: 11, P: 282

All Research & Reviews

News and Comment

ALASCCA: an aspirin a day keeps colorectal cancer away
- David Killock
Research Highlights26 Sept 2025 Nature Reviews Clinical Oncology
P: 1
NeuroGASTRO 2025
- Katrina Ray
Research Highlights22 Sept 2025 Nature Reviews Gastroenterology & Hepatology
P: 1
Diagnosing paediatric coeliac disease
- Jason C. Lin
Research Highlights22 Sept 2025 Nature Reviews Gastroenterology & Hepatology
P: 1
Vaccine for pancreatic and colorectal cancer: phase I AMPLIFY-201 trial
- Jordan Hindson
Research Highlights08 Sept 2025 Nature Reviews Gastroenterology & Hepatology
Volume: 22, P: 672
AI-assisted colonoscopy and risk of endoscopist deskilling
- Katrina Ray
Research Highlights05 Sept 2025 Nature Reviews Gastroenterology & Hepatology
Volume: 22, P: 672
Semaglutide targets MASH molecular pathways beyond weight loss

A proteomic study begins to identify the direct and indirect effects of GLP-1 treatment on metabolic dysfunction-associated steatohepatitis (MASH), and reveals insights into treatment-induced changes in liver histology.
- Maurice Michel
- Jörn M. Schattenberg
News & Views01 Sept 2025 Nature Medicine
Volume: 31, P: 2865-2866

All News & Comment