Fig. 4: IL-5- and IL-10-mediated T cell responses are associated with C9orf72 mutation status and predicted survival.
From: Autoimmune response to C9orf72 protein in amyotrophic lateral sclerosis
a–d, Total (a), IFNγ-mediated (b), IL-5-mediated (c) and IL-10-mediated (d) T cell responses towards C9orf72 in a validation cohort of participants with ALS carrying the C9orf72 mutation (n = 7) or not carrying any mutation linked to an increased risk of ALS (n = 7). e–h, Total (e), IFNγ-mediated (f), IL-5-mediated (g) and IL-10-mediated (h) T cell responses towards C9orf72 in individuals with ALS with a short (n = 6) or long (n = 11) predicted survival time. P values from two-tailed Mann–Whitney tests and geometric mean ± 95% confidence intervals are shown.