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Elaborate machinery for inserting proteins into the outer membrane of bacteria

Bacteria insert proteins into their outer membrane using a highly conserved apparatus known as the β-barrel assembly machinery (BAM). A large group of bacteria with particularly complex outer-membrane proteins is now shown to have a BAM apparatus with a highly unusual composition.
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This is a summary of: Liu, X. et al. A new paradigm for outer membrane protein biogenesis in the Bacteroidota. Nature https://doi.org/10.1038/s41586-025-09532-8 (2025).

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doi: https://doi.org/10.1038/d41586-025-03154-w

Figure 1 is published under a CC BY 4.0 licence.

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