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. 2010;52(11):946-9.

[Interaction between non-histone chromatin protein HMGB1 and linker histone H1]

[Article in Russian]
A V Fonin, Ol'ga V Stepanenko, K K Turoverov, V I Vorob'ev
  • PMID: 21268854

[Interaction between non-histone chromatin protein HMGB1 and linker histone H1]

[Article in Russian]
A V Fonin et al. Tsitologiia. 2010.

Abstract

The fundamental possibility of interaction between non-histone chromatin protein HMGB1 and linker histone H1 was studied in the solutions with different ionic strength by intrinsic UV-fluorescence, far and near-UV CD and spectrophotometry. The obtained data allow us to assume that the increase of histone H1 content in the HMGB1 solutions in a low ionic strength is accompanied by the destruction of HMGB1 associates. The interaction between proteins of HMGB1 and H1 causes the increase in the number of ordered regions in the protein molecules and the minor changes in their tertiary structure.

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