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Detection and characterization of pancreatic and biliary tract cancers using cell-free DNA fragmentomics
BackgroundPlasma cell-free DNA (cfDNA) fragmentomics has demonstrated significant differentiation power between cancer patients and healthy...
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DendroX: multi-level multi-cluster selection in dendrograms
BackgroundCluster heatmaps are widely used in biology and other fields to uncover clustering patterns in data matrices. Most cluster heatmap packages...
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Comut-viz: efficiently creating and browsing comutation plots online
BackgroundComutation plot is a widely used visualization method to deliver a global view of the mutation landscape of large-scale genomic studies....
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Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling
More effective use of targeted anti-cancer drugs depends on elucidating the connection between the molecular states induced by drug treatment and the...
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Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd
Gene expression data are accumulating exponentially in public repositories. Reanalysis and integration of themed collections from these studies may...
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L1000CDS2: LINCS L1000 characteristic direction signatures search engine
The library of integrated network-based cellular signatures (LINCS) L1000 data set currently comprises of over a million gene expression profiles of...
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The characteristic direction: a geometrical approach to identify differentially expressed genes
BackgroundIdentifying differentially expressed genes (DEG) is a fundamental step in studies that perform genome wide expression profiling. Typically,...
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Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool
BackgroundSystem-wide profiling of genes and proteins in mammalian cells produce lists of differentially expressed genes/proteins that need to be...
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ChEA2: Gene-Set Libraries from ChIP-X Experiments to Decode the Transcription Regulome
ChIP-seq experiments provide a plethora of data regarding transcription regulation in mammalian cells. Integrating ChIP-seq studies into a computable...