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  1. Article
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    Detection and characterization of pancreatic and biliary tract cancers using cell-free DNA fragmentomics

    Background

    Plasma cell-free DNA (cfDNA) fragmentomics has demonstrated significant differentiation power between cancer patients and healthy...

    Xiaohan Shi, Shiwei Guo, ... Gang Jin in Journal of Experimental & Clinical Cancer Research
    15 May 2024 Open access
  2. Article
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    DendroX: multi-level multi-cluster selection in dendrograms

    Background

    Cluster heatmaps are widely used in biology and other fields to uncover clustering patterns in data matrices. Most cluster heatmap packages...

    Feiling Feng, Qiaonan Duan, ... Dadong Zhang in BMC Genomics
    02 February 2024 Open access
  3. Article
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    Comut-viz: efficiently creating and browsing comutation plots online

    Background

    Comutation plot is a widely used visualization method to deliver a global view of the mutation landscape of large-scale genomic studies....

    Qiaonan Duan, Weiyi Wang, ... Tongyi Zhang in BMC Bioinformatics
    01 June 2023 Open access
  4. Article
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    Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling

    More effective use of targeted anti-cancer drugs depends on elucidating the connection between the molecular states induced by drug treatment and the...

    Mario Niepel, Marc Hafner, ... Peter K. Sorger in Nature Communications
    30 October 2017 Open access
  5. Article
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    Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd

    Gene expression data are accumulating exponentially in public repositories. Reanalysis and integration of themed collections from these studies may...

    Zichen Wang, Caroline D. Monteiro, ... Avi Ma’ayan in Nature Communications
    26 September 2016 Open access
  6. Article
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    L1000CDS2: LINCS L1000 characteristic direction signatures search engine

    The library of integrated network-based cellular signatures (LINCS) L1000 data set currently comprises of over a million gene expression profiles of...

    Qiaonan Duan, St Patrick Reid, ... Avi Ma’ayan in npj Systems Biology and Applications
    04 August 2016 Open access
  7. Article

    A blueprint of cell identity

    Avi Ma'ayan, Qiaonan Duan in Nature Biotechnology
    09 October 2014
  8. Article
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    The characteristic direction: a geometrical approach to identify differentially expressed genes

    Background

    Identifying differentially expressed genes (DEG) is a fundamental step in studies that perform genome wide expression profiling. Typically,...

    Neil R Clark, Kevin S Hu, ... Avi Ma’ayan in BMC Bioinformatics
    21 March 2014 Open access
  9. Article
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    Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

    Background

    System-wide profiling of genes and proteins in mammalian cells produce lists of differentially expressed genes/proteins that need to be...

    Edward Y Chen, Christopher M Tan, ... Avi Ma’ayan in BMC Bioinformatics
    15 April 2013 Open access
  10. Conference paper

    ChEA2: Gene-Set Libraries from ChIP-X Experiments to Decode the Transcription Regulome

    ChIP-seq experiments provide a plethora of data regarding transcription regulation in mammalian cells. Integrating ChIP-seq studies into a computable...
    Yan Kou, Edward Y. Chen, ... Avi Ma‘ayan in Availability, Reliability, and Security in Information Systems and HCI
    2013
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