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Genomic insights unveil the plasmid transfer mechanism and epidemiology of hypervirulent Klebsiella pneumoniae in Vietnam
Hypervirulent Klebsiella pneumoniae(hvKp) is a significant cause of severe invasive infections in Vietnam, yet data on its epidemiology, population...
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Evolutionary histories and antimicrobial resistance in Shigella flexneri and Shigella sonnei in Southeast Asia
Conventional disease surveillance for shigellosis in developing country settings relies on serotyping and low-resolution molecular typing, which...
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Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia
BackgroundKlebsiella pneumoniaeis a leading cause of bloodstream infection (BSI). Strains producing extended-spectrum beta-lactamases (ESBLs) or...
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Pig Exposure and Health Outcomes in Hospitalized Infectious Disease Patients in Vietnam
Many infectious diseases have a zoonotic origin, and several have had major public health implications. Contact with animals is a known risk factor...
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Phenotypic and genotypic characteristics of ESBL and AmpC producing organisms associated with bacteraemia in Ho Chi Minh City, Vietnam
BackgroundBroad-spectrum antimicrobials are commonly used as empirical therapy for infections of presumed bacterial origin. Increasing resistance to...
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Variation at HLA-DRB1 is associated with resistance to enteric fever
Enteric fever affects more than 25 million people annually and results from systemic infection with Salmonella entericaserovar Typhi or Paratyphi...
