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  1. Article
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    Association between attention-deficit/hyperactivity disorders and intestinal disorders: A systematic review and Meta-analysis

    Patients with attention-deficit hyperactivity disorder (ADHD) reported significantly more constipation and flatulence than healthy controls. An...

    Rita W. Y. Ng, Zigui Chen, ... Margaret Ip in Scientific Reports
    02 June 2025 Open access
  2. Article
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    Geographical migration and fitness dynamics of Streptococcus pneumoniae

    Streptococcus pneumoniaeis a leading cause of pneumonia and meningitis worldwide. Many different serotypes co-circulate endemically in any one...

    Sophie Belman, Noémie Lefrancq, ... Henrik Salje in Nature
    03 July 2024 Open access
  3. Article
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    LOX-1 acts as an N6-methyladenosine-regulated receptor for Helicobacter pylori by binding to the bacterial catalase

    The role of N6-methyladenosine (m6A) modification of host mRNA during bacterial infection is unclear. Here, we show that Helicobacter pylori...

    Judeng Zeng, Chuan Xie, ... William K. K. Wu in Nature Communications
    22 January 2024 Open access
  4. Article
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    Storage stability of lysostaphin solution and its pulmonary delivery

    Methicillin-resistant Staphylococcus aureus(MRSA) has become a leading causative pathogen of nosocomial pneumonia with an alarming in-hospital...

    Ping Zeng, Pengfei Zhang, ... Sharon Shui Yee Leung in Drug Delivery and Translational Research
    17 January 2024 Open access
  5. Article
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    Whole genomes from bacteria collected at diagnostic units around the world 2020

    The Two Weeks in the World research project has resulted in a dataset of 3087 clinically relevant bacterial genomes with pertaining metadata,...

    Sidsel Nag, Gunhild Larsen, ... Frank Moller Aarestrup in Scientific Data
    16 September 2023 Open access
  6. Chapter

    Infection

    Knee joint infection, either within or around the joint, requires an early and specific diagnosis. Reaching this diagnosis is heavily dependent on...
    James Francis Griffith, Margaret Ip in Imaging of the Knee
    2023
  7. Article
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    Colonization with selected antibiotic resistant bacteria among a cohort of Sri Lankan university students

    Background

    Antibiotic Resistance is an imminent global public health threat. Antibiotic resistance emerged in healthcare settings and has now moved on...

    Thilini Munasinghe, Gihani Vidanapathirana, ... Margaret Ip in BMC Infectious Diseases
    15 June 2021 Open access
  8. Article
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    A simple, rapid typing method for Streptococcus agalactiae based on ribosomal subunit proteins by MALDI-TOF MS

    Streptococcus agalactiae (Group B Streptococcus, GBS), is a frequent human colonizer and a leading cause of neonatal meningitis as well as an...

    Julian Rothen, Dulmini Nanayakkara Sapugahawatte, ... Margaret Ip in Scientific Reports
    29 May 2020 Open access
  9. Article
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    Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia

    Background

    Klebsiella pneumoniaeis a leading cause of bloodstream infection (BSI). Strains producing extended-spectrum beta-lactamases (ESBLs) or...

    Kelly L. Wyres, To N. T. Nguyen, ... Kathryn E. Holt in Genome Medicine
    16 January 2020 Open access
  10. Article

    Adaptation of host transmission cycle during Clostridium difficile speciation

    Bacterial speciation is a fundamental evolutionary process characterized by diverging genotypic and phenotypic properties. However, the selective...

    Nitin Kumar, Hilary P. Browne, ... Trevor D. Lawley in Nature Genetics
    12 August 2019
  11. Article
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    Diversity of macaque microbiota compared to the human counterparts

    Studies on the microbial communities in non-human primate hosts provide unique insights in both evolution and function of microbes related to human...

    Zigui Chen, Yun Kit Yeoh, ... Paul K. S. Chan in Scientific Reports
    22 October 2018 Open access
  12. Article

    Differential gene expression in Escherichia coli during aerosolization from liquid suspension

    Comparative transcriptome analysis was used to determine the differentially expressed genes in Escherichia coliduring aerosolization from liquid...

    Tsz Wai Ng, Margaret Ip, ... Ka Man Lai in Applied Microbiology and Biotechnology
    28 May 2018
  13. Article
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    Comparative transcriptomics of multidrug-resistant Acinetobacter baumannii in response to antibiotic treatments

    Multidrug-resistant Acinetobacter baumannii, a major hospital-acquired pathogen, is a serious health threat and poses a great challenge to healthcare...

    Hao Qin, Norman Wai-Sing Lo, ... Ting-Fung Chan in Scientific Reports
    23 February 2018 Open access
  14. Article

    Population structure and virulence gene profiles of Streptococcus agalactiae collected from different hosts worldwide

    Streptococcus agalactiaeis a leading cause of morbidity and mortality among neonates and causes severe infections in pregnant women and nonpregnant...

    Marina Morach, Roger Stephan, ... Sophia Johler in European Journal of Clinical Microbiology & Infectious Diseases
    27 November 2017
  15. Article
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    Activity of temocillin and 15 other agents, including fosfomycin and colistin, against Enterobacteriaceae in Hong Kong

    Limited data are available on temocillin susceptibilities in Enterobacteriaceaefrom Asian countries where antimicrobial resistance is prevalent. The...

    Margaret Ip, Christopher K. Lai, ... Peter Hawkey in European Journal of Clinical Microbiology & Infectious Diseases
    25 August 2017 Open access
  16. Article
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    Incidence and serotype distribution of invasive group B streptococcal disease in young infants: a multi-country observational study

    Background

    Group B Streptococcus (GBS) is a leading cause of serious infection in very young infants. Robust incidence data from many geographic...

    Luis Rivera, Xavier Sáez-Llorens, ... Karen S. Slobod in BMC Pediatrics
    01 October 2015 Open access
  17. Article
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    Comparative genomics of methicillin-resistant Staphylococcus aureus ST239: distinct geographical variants in Beijing and Hong Kong

    Background

    The ST239 lineage is a globally disseminated, multiply drug-resistant hospital-associated methicillin-resistant Staphylococcus aureus...

    Zheng Wang, Haokui Zhou, ... Margaret Ip in BMC Genomics
    26 June 2014 Open access
  18. Article
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    Genotypes and virulence in serotype K2 Klebsiella pneumoniae from liver abscess and non-infectious carriers in Hong Kong, Singapore and Taiwan

    In Klebsiella pneumoniae liver abscess (KP-LA), K. pneumoniae K2 is the most frequently isolated serotype after K1, but this serotype has been much...

    Jung-Chung Lin, Tse Hsien Koh, ... L Kristopher Siu in Gut Pathogens
    12 June 2014 Open access
  19. Article
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    Application of a target enrichment-based next-generation sequencing protocol for identification and sequence-based prediction of pneumococcal serotypes

    Background

    The use of whole-genome sequencing in microbiology at a diagnostic level, although feasible, is still limited by the expenses associated...

    Veranja Liyanapathirana, Irene Ang, ... Margaret Ip in BMC Microbiology
    10 March 2014 Open access
  20. Article

    Childhood Pneumococcal Diseases and Serotypes: Can Vaccines Protect?

    Objectives

    To describe pneumococcal diseases in pediatric intensive care unit (PICU) and non-PICU patients.

    Methods

    The clinical, serotypes, and...

    Kam Lun Hon, Margaret Ip, ... Ting Fan Leung in The Indian Journal of Pediatrics
    16 September 2010
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