Skip to main content
Log in

Deep learning algorithm performance evaluation in detection and classification of liver disease using CT images

  • Published:
Multimedia Tools and Applications Aims and scope Submit manuscript

Abstract

To diagnose the liver diseases computed tomography images are used. Most of the time even experienced radiologists find it very tough to note the type, size, and severity of the tumor from computed tomography images due to various complexities involved around the liver. In recent years it is very much essential to develop a computer-assisted imaging technique to diagnose liver disease in turn which improves the diagnosis of a doctor. This paper explains a novel deep learning model for detecting a liver disease tumor and its classification. Tumor from computed tomography images has been classified between Metastasis and Cholangiocarcinoma. We demonstrate that our model predominantly performs very well concerning the accuracy, dice similarity coefficient, and specificity parameters compared to well-known existing algorithms, and adapts very well for different datasets. A dice similarity coefficient value of 98.59% indicates the supremacy of the model.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+
from $39.99 /Month
  • Starting from 10 chapters or articles per month
  • Access and download chapters and articles from more than 300k books and 2,500 journals
  • Cancel anytime
View plans

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11

Similar content being viewed by others

Data availability

The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.

References

  1. Ahmad M et al (2019) Deep belief network modeling for automatic liver segmentation. IEEE Access 7:20585–20595

    Article  Google Scholar 

  2. Balagourouchetty L, Pragatheeswaran JK, Pottakkat B, Ramkumar G (2020) GoogLeNet-based ensemble FCNet classifier for focal liver lesion diagnosis. IEEE J Biomed Health Inform 24(6):1686–1694. https://doi.org/10.1109/JBHI.2019.2942774.18

    Article  Google Scholar 

  3. Bevilacqua V et al (2017) A novel approach for hepatocellular carcinoma detection and classification based on triphasic CT protocol. In: A novel approach for hepatocellular carcinoma detection and classification based on triphasic CT protocol, pp 1856–1863

  4. Bharti P, Mittal D, Ananthasivan R (2018) Preliminary study of chronic liver classification on ultrasound images using an ensemble model. Ultrason Imaging 40(6):357–379. https://doi.org/10.1177/0161734618787447.12

    Article  Google Scholar 

  5. Chen D, Huang M, Li W (2019) Knowledge-powered deep breast tumor classification with multiple medical reports. IEEE/ACM Trans Comput Biol Bioinform 18(3):891–901

    Article  Google Scholar 

  6. Cholangiocarcinoma cancer. Available online: https://radiopaedia.org/articles/cholangiocarcinoma. Accessed on 10 Dec 2021

  7. Das A, Rajendra Acharya U, Panda SS, Sabut S (2018) Deep learning based liver cancer detection using watershed transform and Gaussian mixture model techniques. Cogn Syst Res. https://doi.org/10.1016/j.cogsys.2018.12.009

  8. Das A, Das P, Panda SS, Sabut S (2019) Detection of liver cancer using modified fuzzy clustering and decision tree classier in CT images. Pattern Recognit Image Anal 29(2):201–211. https://doi.org/10.1134/S1054661819020056.24

    Article  Google Scholar 

  9. Gaber A, Youness HA, Hamdy A, Abdelaal HM, Hassan AM (2022) Automatic classification of fatty liver disease based on supervised learning and genetic algorithm. Appl Sci 12:521. https://doi.org/10.3390/app12010521

    Article  Google Scholar 

  10. Gatos I, Tsantis S, Spiliopoulos S, Karnabatidis D, Theotokas I, Zoumpoulis P, Loupas T, Hazle JD, Kagadis GC (2017) A machine-learning algorithm toward color analysis for chronic liver disease classification, employing ultrasound shear wave elastography. Ultrasound Med Biol 43:1797–1810

    Article  Google Scholar 

  11. Gogate M, Dashtipour K, Bell P, Hussain A (2020) Deep neural network driven bi-natural audio-visual speech separation. In: Proceedings of the 2020 International Joint Conference on Neural Networks (IJCNN), Glasgow, pp 1–7

  12. Hosseinzadeh M, Koohpavehxadeh J, Bali AO, Asghari P, Souri A, Mazaherinezhad A, Bolouli M, Rawassizadeh R (2021) A diagnostic prediction model for chronic kidney disease in internet of things platform. Multimed Tools Appl 80:16933–16950. https://doi.org/10.1007/s11042-020-09409-4

    Article  Google Scholar 

  13. Iraji MS, Derakhshi MRF, Tanha J (2021) Covid-19 detection using deep convolutional neural networks and binary differential algorithms based feature selection from Xray images. Hindawi complexity 2021:9973277. https://doi.org/10.1155/2021/9973277

    Article  Google Scholar 

  14. Jacob J, Mathew JC, Mathew J, Issac E (2018) Diagnosis of liver disease using machine learning techniques. Int Res J Eng Technol 5(04)

  15. Jaganathan K, Tayara H, Chong KT (2021) Prediction of drug-induced liver toxicity using SVM and optimal descriptor sets. Int J Mol Sci 22:8073

    Article  Google Scholar 

  16. Joloudari JH, Saadatfar H, Dehzangi A, Shamshirband S (2019) Computer-aided decision-making for predicting liver disease using PSO-based optimized SVM with feature selection. Inform Med Unlocked 17:100255

    Article  Google Scholar 

  17. Kahn RA, Luo Y, Wu F-X (2022) Machine learning based liver disease diagnosis: a systematic review. Neurocomputing 468:492–509. https://doi.org/10.1016/j.neucom.2021.08.138

    Article  Google Scholar 

  18. Krishnan A, Mittal D (2021) Ensembled liver cancer detection and classification using CT images. Proc Inst Mech Eng H 235(2):232–244

    Article  Google Scholar 

  19. Liver Metastasis. Available online: https://www.healthline.com/health/liver-metastases. Accessed on 14 Dec 2018

  20. Maghdid HS, Asaad AT, Ghafoor KZ, Sadiq AS, Khan MK (2020) Diagnosing COVID-19 pneumonia from X-Ray and CT images using deep learning and transfer learning algorithms. arXiv preprint arXiv:2004.00038

  21. Metastatic Cancer. Available online: http://www.cancer.ca/en/cancerinformation/cancer-type/metastatic-cancer/liver-metastases/?region=on. Accessed on 10 December 2021

  22. Miriam E (2013) Tucker The Liver Meeting 2013: American Association for the Study of Liver Diseases (AASLD). Medscape. Available online: https://www.medscape.com/viewarticle/813788. Accessed on 14 Dec 2018

  23. Mostafa F, Hasan E, Williamson M, Khan H (2021) Statistical machine learning approaches to liver disease prediction. Livers 1:294–312

    Article  Google Scholar 

  24. Muthuswamy J (2019) Extraction and classification of liver abnormality based on neutrosophic and SVM classifier. In: Progress in advanced computing and intelligent engineering. Springer, pp 269–279. https://doi.org/10.1007/978-981-13-1708-825.24

  25. Phan DV, Chan CL, Li AA, Chien TY, Nguyen VC (2020) Liver cancer prediction in a viral hepatitis cohort: a deep learning approach. Int J Cancer 147:2871–2878

    Article  Google Scholar 

  26. Rahamani AM, Babaei Z, Souri A (2021) Event-driven IoT architecture for data analysis of reliable healthcare application using complex event processing. Clust Comput 24:1347–1360, Springer. https://doi.org/10.1007/s10586-020-03189-w

    Article  Google Scholar 

  27. Rajathi GI, Jiji GW (2019) Chronic liver disease classification using hybrid whale optimisation with simulated annealing and ensemble classifier. Symmetry 11:33. https://doi.org/10.3390/sym11010033

    Article  Google Scholar 

  28. Renukadevi NT (2021) Performance evaluation of hybrid machine learning algorithms for medical image classification. Advanced soft computing techniques in data science, IoT and cloud computing, studies in big data volume 89. Springer, Cham. https://doi.org/10.1007/978-3-030-75657-4_12

  29. Sung YS, Park B, Park HJ, Lee SS (2021) Radiomics and deep learning in liver diseases. J Gastroenterol Hepatol 36:561–568

    Article  Google Scholar 

  30. Yamakawa M, Shiina T, Nishida N, Kudo M (2019) Computer aided diagnosis system developed for ultrasound diagnosis of liver lesions using deep learning. IEEE International Ultrasonics Symposium, IUS 2019-Octob, pp 2330–2333. https://doi.org/10.1109/ULTSYM.2019.8925698.21

  31. Zhang T, Zhang S, Jin C et al (2021) A predictive model based on the gut microbiota improves the diagnostic effect in patients with Cholangiocarcinoma. Front Cell Infect Microbiol. https://doi.org/10.3389/fcimb.2021.751795

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to R. V. Manjunath.

Ethics declarations

Ethics approval and consent to participate

We comply to the ethical standards. We give our consent to participate.

Consent for publication

 All the authors are giving consent to publish.

Informed consent

Not applicable.

Research involving human participation and/or animals

Not applicable.

Competing interests

No conflict of interest to declare.

Conflict of interest

The authors declare no conflict of interest, financial or otherwise.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Manjunath, R.V., Ghanshala, A. & Kwadiki, K. Deep learning algorithm performance evaluation in detection and classification of liver disease using CT images. Multimed Tools Appl 83, 2773–2790 (2024). https://doi.org/10.1007/s11042-023-15627-z

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11042-023-15627-z

Keywords