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Fig. 3 | Translational Neurodegeneration

Fig. 3

From: Extensive frontal focused ultrasound mediated blood–brain barrier opening for the treatment of Alzheimer’s disease: a proof-of-concept study

Fig. 3

The targets and MRI demonstration of BBB opening and closure in Patient 3. Immediately post-FUS gadolinium-enhanced T1 MRI showed that parenchyme at target was well enhanced, indicating the successful BBB opening. Afterwards, this area did not show enhancement in MRI at 3 months post-procedure, indicating that the BBB was  temporarily opened and closed

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