Fig. 2

Unsupervised clustering analysis of tumor cells and cancer-associated fibroblasts (CAFs) in PDAC primary tumors and metastatic lesions. a Tumor cells in the primary tumors are mostly segregated by patients. b Tumor cells in the metastatic lesions also cluster by patients. c Three major clusters are formed by CAFs from primary tumors. d CAFs from different patients are mixed in the different clusters