Faced with skyrocketing costs for developing new drugs, researchers are looking at ways to repurpose older ones — and even some that failed in initial trials.
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References
Singh, N. et al. Nature Commun. http://dx.doi.org/10.1038/ncomms2320 (2013).
Singh, N. et al. Neuropsychopharmacology 41, 1768–1778 (2016).
Scannell, J. W., Blanckley, A., Boldon, H. & Warrington, B. Nature Rev. Drug Discov. 11, 191–200 (2012).
American Chemical Society. International Year of Chemistry 2011: Activities Report of the American Chemical Society (ACS, 2011); available at http://go.nature.com/1tbzmxn
Lekka, E., Deftereos, S. N., Persidis, A., Persidis, A. & Andronis, C. Drug Discov. Today Ther. Strateg. 8, 103–108 (2011).
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Nosengo, N. Can you teach old drugs new tricks?. Nature 534, 314–316 (2016). https://doi.org/10.1038/534314a
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DOI: https://doi.org/10.1038/534314a
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