JMIR Dermatology

Acral Persistent Papular Mucinosis (APPM) is a localized variant of lichen myxedematosus (LM) characterized by asymptomatic, flesh-colored papules primarily distributed on the hands and forearms. This chronic dermatosis, distinct from generalized mucinosis due to its lack of systemic involvement, remains underreported in medical literature.

Medical students' comparison of dermatological cases generated by AI versus those created without AI revealed that AI-created cases were characterized by detailed case descriptions, analysis of medical history, clinical examinations, but lacked the depth, clinical relevance, and motivational elements found in non-AI cases, which were shorter, presented clinical dilemmas and included challenging scenarios that students found more educational and engaging.

Artificial intelligence (AI) and telemedicine have great potential to transform dermatology care delivery, but patient perspectives on these technologies have not been systematically compared.

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Xylazine has been associated with skin wounds. The rising prevalence of xylazine and its debated role in wound causation have sparked concerns among public health professionals, medical experts, and people who use drugs (PWUDs).

Dermal fillers have gained increasing popularity for their ability to enhance facial symmetry, restore volume, and improve skin texture. However, their use in cancer patients undergoing active chemotherapy and radiation therapy poses unique challenges, as these treatments can alter both the safety profile and efficacy of filler procedures. Chemotherapy can interfere with normal wound healing and immune responses, warranting a more cautious and individualized approach when considering dermal fillers in this population. Although rare, dermal fillers have been associated with adverse outcomes in a limited number of reports, including cellulitis, ASIA, and a possible predisposition to malignancy. Other effects include localized inflammatory, systemic hypersensitivity, and delayed granulomatous formation, and these could be more severe in patients undergoing antineoplastic therapy. Furthermore, chemotherapy is often paired with adjuvant radiation therapy in cancer treatment, making it important to note the potential changes radiation can have on the skin. More research is needed to examine the direct interactions of chemotherapy and radiation on various filler materials injected within the skin, and how these can alter one's risk of adverse effects. The lack of research on this topic further emphasizes that clinicians should thoroughly educate patients receiving chemotherapy and adjuvant radiation treatment about the heightened potential risks associated with dermal filler injections and treatment regimens should be planned accordingly to minimize any adverse events.

This research letter evaluated the quality and readability of hidradenitis suppurativa (HS) websites found on Google and Bing by utilizing the DISCERN Instrument and Flesch-Kincaid Readability metrics. Comprehensive and reliable articles can lead to increased knowledge about HS, and further enhance physician-patient relationships and shared decision making. This study’s aim was to identify reliable resources to help bridge knowledge gaps and support informed discussions on management and treatment options.

Our study demonstrated the ability of ChatGPT-4 to answer 77.5% of all sampled text-based board review type questions correctly. Questions requiring recall of factual information were answered correctly most often, with slight decreases in correctness as higher-order thinking requirements increased. Improvements to ChatGPT’s visual diagnostics capabilities will be required before it can be used reliably for clinical decision-making and visual diagnostics

Delusional parasitosis (DP) is a rare psychotic disorder where individuals firmly believe they are infested with parasites despite no medical evidence. It may be shared among close contacts, termed folie à deux when two individuals are affected or folie à trois when three individuals share the delusion. DP’s somatic focus often leads patients to dermatologists, causing delayed diagnosis and unnecessary antiparasitic treatments. Herein, we present two familial cases of shared DP. In both cases, patients exhibited the matchbox sign, presenting non-parasitic materials as "evidence" of infestation. Dermatological and psychiatric evaluations excluded organic causes, diagnosing primary DP. Treatment with antipsychotic medications led to symptom remission. Psychoeducation was critical in preventing relapse in secondary cases. DP with shared delusions is often misdiagnosed, requiring dermatologists to recognize it early. A multidisciplinary approach, combining psychiatric care and psychoeducation, is essential for effective management and for preventing reinforcement of delusional beliefs.

Based on editor feedback, no changes need to be made for the abstract.

Our study develops a GPT assistant for neurocutaneous diseases with a custom knowledge base, tests its ability to answer common patient questions, and shows that a GPT using retrieval augmentation generation can improve the readability of patient educational material without prompting a specific reading level.

Acne vulgaris (AV) is one of the most common skin disorders, with a peak incidence in adolescence and early adulthood. Topical treatments are usually used for mild to moderate AV, however a lack of adherence to topical treatment is seen in patients due to various reasons. Therefore, personalised skincare recommendations may be beneficial for treating mild-to-moderate acne vulgaris (AV).