Abstract
There have been many major developments in the use of augmented reality (AR), virtual reality (VR), and mixed reality (MR) technologies in the context of global surgical research, yet few reports on the trends in this field have been published to date. This study was therefore designed to explore these worldwide trends in this clinically important field. Relevant studies published from 1 January 2009 through 13 October 2020 were retrieved from the Science Citation Index-Expanded (SCI-E) tool of the Web of Science database. Bibliometric techniques were then used to analyze the resultant data, with visual bibliographic coupling, co-authorship, co-citation, co-occurrence, and publication trend analyses subsequently being conducted with GraphPad Prism 8 and with the visualization of similarities (VOS) software tool. There is no patient and public involved. In total, 6221 relevant studies were incorporated into this analysis. At a high level, clear global annual increases in the number of publications in this field were observed. The USA made the greatest contributions to this field over the studied period, with the highest H-index value, the most citations, and the greatest total link strength for analyzed publications. The country with the highest number of average citations per publication was Scotland. The Surgical Endoscopy And Other Interventional Techniques journal contributed the greatest number of publications in this field. The University of London was the institution that produced the greatest volume of research in this field. Overall, studies could be broadly classified into five clusters: Neurological Research, Surgical Techniques, Technological Products, Rehabilitative Medicine, and Clinical Therapy. The trends detected in the present analysis suggest that the number of global publications pertaining to the use of AR, VR, and MR techniques in surgical research is likely to increase in the coming years. Particular attention should be paid to emerging trends in related fields including MR, extended reality, head-mounted displays, navigation, and holographic images.























Similar content being viewed by others

Data Sharing
No additional data are available.
Abbreviations
- IF:
-
Impact factor
- TLS:
-
Total link strength
- WOS:
-
Web of Science
References
Mertz L (2019) Virtual reality pioneer Tom Furness on the past, present, and future of VR in health care. IEEE Pulse 10(3):9–11. https://doi.org/10.1109/MPULS.2019.2911808
Sutherland J et al (2019) Applying modern virtual and augmented reality technologies to medical images and models. J Digit Imaging 32(1):38–53. https://doi.org/10.1007/s10278-018-0122-7
Sakai D et al (2020) Augmented, virtual and mixed reality in spinal surgery: a real-world experience. J Orthop Surg. https://doi.org/10.1177/2309499020952698
Saito Y et al (2020) Intraoperative 3D hologram support with mixed reality techniques in liver surgery. Ann Surg 271(1):e4–e7. https://doi.org/10.1097/SLA.0000000000003552
Yoshida S et al (2019) Mixed reality computed tomography-based surgical planning for partial nephrectomy using a head-mounted holographic computer. Int J Urol 26(6):681–682. https://doi.org/10.1111/iju.13954
Verhey JT, et al. (2020) Virtual, augmented, and mixed reality applications in orthopedic surgery. Int J Med Robot 16(2):e2067. https://doi.org/10.1002/rcs.2067
Hu HZ et al (2019) Application and prospect of mixed reality technology in medical field. Curr Med Sci 39(1):1–6. https://doi.org/10.1007/s11596-019-1992-8
Mao X, et al. (2020) The status and trends of coronavirus research: a global bibliometric and visualized analysis. Medicine 99(22):e20137. https://doi.org/10.1097/MD.0000000000020137
Tijssen RJ, Winnink J (2016) Twenty-first century macro-trends in the institutional fabric of science: bibliometric monitoring and analysis. Scientometrics 109(3):2181–2194. https://doi.org/10.1007/s11192-016-2041-z
Ekinci S et al (2015) Letter to the Editor regarding analysis of changing paradigms of management in 179 patients with spinal tuberculosis during a 12-year period and proposal of a new management algorithm. World Neurosurg 84(6):2072. https://doi.org/10.1016/j.wneu.2014.12.003
Pu QH, Lyu QL, Su HY (2016) Bibliometric analysis of scientific publications in transplantation journals from Mainland China, Japan, South Korea and Taiwan between 2006 and 2015. BMJ Open 6(8): p. e011623. https://doi.org/10.1136/bmjopen-2016-011623
Chien TW, et al. (2019) Choropleth map legend design for visualizing the most influential areas in article citation disparities: a bibliometric study. Medicine (Baltimore) 98(41): p. e17527. https://doi.org/10.1097/MD.0000000000017527
Zyoud SH (2016) Global research trends of Middle East respiratory syndrome coronavirus: a bibliometric analysis. BMC Infect Dis 16:255. https://doi.org/10.1186/s12879-016-1600-5
Wang B et al (2019) The state of exosomes research: a global visualized analysis. Biomed Res Int 2019:1495130. https://doi.org/10.1155/2019
Cislo-Pakuluk A, Marycz K (2017) A promising tool in retina regeneration: current perspectives and challenges when using mesenchymal progenitor stem cells in veterinary and human ophthalmological applications. Stem Cell Rev Rep 13(5):598–602. https://doi.org/10.1007/s12015-017-9750-4
Zhai X, et al. (2017) Global research trends in spinal ultrasound: a systematic bibliometric analysis. BMJ Open 7(10):e015317. https://doi.org/10.1136/bmjopen-2016-01531717
Aggarwal A et al (2016) The state of lung cancer research: a global analysis. J Thorac Oncol 11(7):1040–1050. https://doi.org/10.1016/j.jtho.2016.03.010
Pei W et al (2019) Research trends of acupuncture therapy on insomnia in two decades (from 1999 to 2018): a bibliometric analysis. BMC Complement Altern Med 19(1):225. https://doi.org/10.1186/s12906-019-2606-519
Zou X, Yue WL, Vu HL (2018) Visualization and analysis of mapping knowledge domain of road safety studies. Accid Anal Prev 118:131–145. https://doi.org/10.1016/j.aap.2018.06.010
Bertoli-Barsotti L, Lando T (2017) A theoretical model of the relationship between the h-index and other simple citation indicators. Scientometrics 111(3):1415–1448. https://doi.org/10.1007/s11192-017-2351-9
Mao X, et al. (2020) A global bibliometric and visualized analysis in the status and trends of subchondral bone research. Medicine (Baltimore) 99(22):e20406. https://doi.org/10.1097/MD.0000000000020406
Mao XJ, et al. (2020) The status and trends of coronavirus research: a global bibliometric and visualized analysis. Medicine. https://doi.org/10.1097/MD.0000000000020137
Zhai X, Wang Q, Li M (2016) Tu Youyou’s Nobel Prize and the academic evaluation system in China. The Lancet 387(10029). https://doi.org/10.1016/S0140-6736(16)30261-6
Stefan P et al (2018) Team training and assessment in mixed reality-based simulated operating room: current state of research in the field of simulation in spine surgery exemplified by the ATMEOS project. Unfallchirurg 121(4):271–277. https://doi.org/10.1007/s00113-018-0467-x
Wu X et al (2018) Mixed reality technology launches in orthopedic surgery for comprehensive preoperative management of complicated cervical fractures. Surg Innov 25(4):421–422. https://doi.org/10.1177/1553350618761758
Lu K et al (2018) Use of short message service and smartphone applications in the management of surgical patients: a systematic review. Telemed J E Health 24(6):406–414. https://doi.org/10.1089/tmj.2017.0123
Wu X et al (2018) Mixed reality technology-assisted orthopedics surgery navigation. Surg Innov 25(3):304–305. https://doi.org/10.1177/1553350618771413
Sauer IM et al (2017) Mixed reality in visceral surgery: development of a suitable workflow and evaluation of intraoperative use-cases. Ann Surg 266(5):706–712. https://doi.org/10.1097/SLA.0000000000002448
Incekara F et al (2018) Clinical feasibility of a wearable mixed-reality device in neurosurgery. World Neurosurg 118:e422–e427. https://doi.org/10.1016/j.wneu.2018.06.208
Lee SC et al (2017) Multi-modal imaging, model-based tracking, and mixed reality visualisation for orthopaedic surgery. Healthc Technol Lett 4(5):168–173. https://doi.org/10.1049/htl.2017.0066
Cabana F et al (2016) Is an in-home telerehabilitation program for people with proximal humerus fracture as effective as a conventional face-to face rehabilitation program? A study protocol for a noninferiority randomized clinical trial. BMC Sports Sci Med Rehabil 8(1):27. https://doi.org/10.1186/s13102-016-0051-z
Wang S, et al. (2017) Augmented reality as a telemedicine platform for remote procedural training. Sensors. https://doi.org/10.3390/s17102294
Negrillo-Cárdenas J, Jiménez-Pérez J-R, Feito FR (2020) The role of virtual and augmented reality in orthopedic trauma surgery: from diagnosis to rehabilitation. Computer Methods and Programs in Biomedicine. https://doi.org/10.1016/j.cmpb.2020.105407
Drouin S et al (2016) IBIS: an OR ready open-source platform for image-guided neurosurgery. Int J Comput Assist Radiol Surg 12(3):363–378. https://doi.org/10.1007/s11548-016-1478-0
Sayadi LR et al (2019) The new frontier: a review of augmented reality and virtual reality in plastic surgery. Aesthet Surg J 39(9):1007–1016. https://doi.org/10.1093/asj/sjz04336
Gorbanev I et al (2018) A systematic review of serious games in medical education: quality of evidence and pedagogical strategy. Med Educ Online 23(1):1438718. https://doi.org/10.1080/10872981.2018.1438718
Southworth MK, Silva JR, Silva JNA (2020) Use of extended realities in cardiology. Trends Cardiovasc Med 30(3):143–148. https://doi.org/10.1016/j.tcm.2019.04.005
Funding
This study was supported by a grant from National Nature Science Foundation of China (No. 81802204).
Author information
Authors and Affiliations
Contributions
Xin Lv and Bin Wang conceived the research; Jing Zhang and Na Yu collected the data and prepared the manuscript; Jing Zhang and Na Yu analyzed the data; Na Yu provided techniques and advice.
Corresponding author
Ethics declarations
Ethics Approval
Ethical approval of the study was not necessary.
Competing Interests
The authors declare no competing interests.
Patient and Public Involvement
No patient involved. This review was not registered. The protocol was not prepared.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Zhang, J., Yu, N., Wang, B. et al. Trends in the Use of Augmented Reality, Virtual Reality, and Mixed Reality in Surgical Research: a Global Bibliometric and Visualized Analysis. Indian J Surg 84 (Suppl 1), 52–69 (2022). https://doi.org/10.1007/s12262-021-03243-w
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12262-021-03243-w